Results 51 to 60 of about 239,970 (262)
Background Previous research has indicated that depressive symptoms may contribute to an escalation in smoking intensity; however, our knowledge regarding the underlying mediating and moderating mechanisms of this association among ethnic minorities ...
Xinping Wang +7 more
doaj +1 more source
IntroductionMycoplasma hyopneumoniae (Mhp) infection significantly challenges Guangxi’s pig farms, yet its prevalence and molecular characteristics remain poorly understood.
Ying Zhou +15 more
doaj +1 more source
In 1997, the Centers for Disease Control and Prevention, the Mexican Secretariat of Health, and border health officials began the development of the Border Infectious Disease Surveillance (BIDS) project, a surveillance system for infectious diseases ...
Michelle Weinberg +23 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Genetic Evolution of H9N2 Avian Influenza Virus in Guangxi, China
H9N2 avian influenza virus (AIV) is widely prevalent in poultry in China. To understand the genetic characteristics and evolution of H9N2 AIVs in Guangxi, southern China, the complete genomes of H9N2 AIVs from 1999–2023 were systematically analysed ...
Minxiu Zhang +15 more
doaj +1 more source
Border Disease Virus among Chamois, Spain
Approximately 3,000 Pyrenean chamois (Rupicapra pyrenaica pyrenaica) died in northeastern Spain during 2005–2007. Border disease virus infection was identified by reverse transcription–PCR and sequencing analysis.
Ignasi Marco +6 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Starting in 2015, the widespread prevalence of hydropericardium-hepatitis syndrome (HHS) has led to considerable financial losses within China’s poultry farming industry.
You Wei +25 more
doaj +1 more source
Border disease of sheep and goats.
Border disease (BD) is a congenital virus disease of sheep and goats first reported in 1959 from the border region of England and Wales. BD virus (BDV) is a pestivirus in the genus Flaviviridae and is closely related to classical swine fever virus and bovine virus diarrhoea virus (BVDV).
F. Nettleton, Peter +3 more
openaire +2 more sources

