Results 71 to 80 of about 3,495 (284)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Art of Internet Mapping: A Comprehensive Guide to Regional Internet Topology Mapping at the Autonomous System Level

open access: yesJournal of Information Systems Engineering and Business Intelligence
Background: Internet topology is studied more by researchers on global internet coverage compared to limited regional coverage. However, some studies also see the importance of studying internet topology in certain countries or regions.
Timotius Witono   +2 more
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Design, implementation and formal verification of BGP proxy for mimic router

open access: yesTongxin xuebao, 2023
To ensure the safety and correctness of the critical ‘mimic bracket’ components such as protocol proxies of mimic routers, a BGP (border gateway protocol) proxy was designed and implemented, and formal methods were applied to verify the safety and ...
Jin ZHANG   +5 more
doaj   +2 more sources

A Hybrid Model for BGP Anomaly Detection Using Median Absolute Deviation and Machine Learning

open access: yesIEEE Open Journal of the Communications Society
Detecting anomalies in the Border Gateway Protocol (BGP) has proved relevant in the cybersecurity field due to the protocol’s critical role in the Internet’s infrastructure. BGP vulnerabilities can lead to major disruptions and connectivity
Maria Andrea Romo-Chavero   +4 more
doaj   +1 more source

Securing the Border Gateway Protocol: A Status Update [PDF]

open access: yes, 2003
The Border Gateway Protocol (BGP) is a critical component of the Internet routing infrastructure, used to distribute routing information between autonomous systems (ASes). It is highly vulnerable to a variety of malicious attacks and benign operator errors.
openaire   +1 more source

Border gateway protocol monitoring system can be cost effective

open access: yesIET Communications, 2011
Network measurement projects such as NLANR, Routeviews and RIPE have greatly advanced people's ability to understand, manage and engineer the Internet. Meanwhile, the significant maintenance fee to support such monitoring infrastructures motivates us to think about a cost-effective way to manage these systems.
Chen, Kai, Hu, C.
openaire   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

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