Results 91 to 100 of about 12,804,735 (261)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Border(ing)s. A Border-Studies Perspective [PDF]

open access: yes
peer reviewedIn both migration studies and border studies, borders are often unquestioned and taken for granted. Increasingly, however, borders are seen as resulting from or resulting in processes and ‘performing’ as powerful agents.
WILLE, Christian
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Border Health Strategic Initiative: Overview and Introduction to a Community-based Model for Diabetes Prevention and Control

open access: yesPreventing Chronic Disease, 2005
This article describes an effort to develop and implement a comprehensive, community-based approach to diabetes prevention and control in selected communities along the U.S.-Mexico border. The U.S.
Stuart J. Cohen, EdD, Maia Ingram
doaj  

Cross-border human mobility and malaria prevalence in Western Ethiopia: A case of the Kurmuk District

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Cross-border population movement complicates malaria control, especially for countries like Ethiopia that aim for elimination. Kurmuk District, on the Ethiopia–Sudan border, faces elevated risk due to frequent human mobility, ecological ...
Zalalam Olani   +9 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Cremian Congo Hemorrhagic Fever Outbreak Jabbi, Aug 2023

open access: yesInternational Journal of Infectious Diseases
Introduction: In a public health rapid response to a confirmed case of Crimean-Congo Hemorrhagic Fever(CCHF) through ELISA/PCR involving a male cattle farmer, aged 51 and subsequent death of the patient was investigated to assess the situation, event ...
Dr Zeba Nasir   +2 more
doaj   +1 more source

The Other US Border: Health Insurance Coverage Among Latino Immigrants In Puerto Rico. [PDF]

open access: yesHealth Aff (Millwood), 2021
Rivera-González AC   +6 more
europepmc   +1 more source

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