Results 71 to 80 of about 12,804,735 (261)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Eurohealth: EU cross-border health care collaboration

, 2013
52 p.This issue of Eurohealth starts with an overview that examines the complex reasons why cross-border care is needed and the driving factors that have underpinned the eventual passage of the new EU Directive on the application of patients’ rights in ...
European Observatory on Health Systems and Policies
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Using Community Indicators to Assess Nutrition in Arizona-Mexico Border Communities

Preventing Chronic Disease, 2005
Introduction Community indicators are used to measure and monitor factors that affect the well-being of a community or region. Community indicators can be used to assess nutrition.
Jacob Abarca, PharmD, Sulabha Ramachandran, MS   +1 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

IPH response to the Joint Committee on Health and Children and members of the Northern Ireland Assembly on “Cross-border cooperation on healthcare”

, 2012
The Institute of Public Health in Ireland were asked to submit a paper on 'Cross-border cooperation on healthcare' for a joint meeting between the Oireachtas Joint Committee on Health and Children and the Northern Ireland Assembly Health ...
Institute of Public Health in Ireland (IPH)
core   +1 more source

Palliative care preparedness among undergraduate nursing students in Northern Saudi Arabia: a cross-sectional study of Knowledge, Attitudes, and Spiritual Care

BMC Palliative Care
Background Palliative care is a core component of holistic nursing practice, yet international and regional evidence indicates persistent gaps in nursing students’ preparedness, particularly in knowledge, attitudes, and spiritual care competence.
Manal Hassan Baqeas, Fathia Ahmed Mersal, Ibrahim Naif Alenezi, Faisal Khalaf Alanazi, Amal Ahmed Elbilgahy   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Quality of life and associated factors among naturally postmenopausal women in Arar Saudi Arabia

Scientific Reports
This study aimed to assess menopause-specific quality of life among naturally postmenopausal women in Arar City, Saudi Arabia, and to examine its association with selected sociodemographic, reproductive, and health-related characteristics.
Fathia Ahmed Mersal, Ateya Megahed Ibrahim, Fathia Gamal Elsaid Hassabelnaby, Heba Ahmed Osman Mohamed, Rasmia Abd El Sattar Ali, Safaa Ibrahim Ahmed, Anu Sam Jacob   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source