Results 51 to 60 of about 447,397 (301)

The upcoming New Pact on Migration and Asylum: Will it be up to the challenge? EPC Discussion Paper 29 April 2020 [PDF]

, 2020
A courageous and ambitious New Pact on Migration and Asylum is one that strengthens the right to asylum; sets the conditions for more equal relationships with third countries when it comes to managing migration; and puts forward a mechanism that can ...
Diez, Olivia Sundberg, Neidhardt, Alberto-Horst   +1 more
core  

The Border Between Seeing and Thinking

, 2023
Abstract This book argues that there is a joint in nature between seeing and thinking, perception, and cognition. Perception is constitutively iconic, nonconceptual, and nonpropositional, whereas cognition does not have these properties constitutively. The book does not appeal to “intuitions,” as is common in philosophy, but to empirical
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An ex post facto study of critical thinking skills in mathematics learning based on school geography

Al-Jabar
Background: Educational disparities in Indonesia necessitate a comprehensive evaluation of students' critical thinking skills across various geographical regions, including highlands, border areas, and lowlands, to address potential educational ...
Iik Nurhikmayati, Nanang Priatna, Jarnawi Afgani Dahlan, Sona Minasyan   +3 more
doaj   +1 more source

Snapshots From the Margins: Transgressive Cosmopolitanisms in Europe [PDF]

, 2014
Right-wing parties and governments in Europe have recently expressed greater hostility towards cultural pluralism, at times officially denunciating multiculturalism, and calling for the closure of borders and denial of rights to non-European nationals ...
Baban, Feyzi, Rygiel, Kim
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Dead Heat For President In NH 11/03/2012 [PDF]

, 2012
President Barack Obama and former Massachusetts Governor Mitt Romney are tied in New Hampshire as the campaign enters the final weekend. The race for Governor remains too close to call with Democrat Maggie Hassan holding a narrow advantage over ...
Survey Center, UNH
core   +1 more source

Everyday cosmopolitanism in representations of Europe among young Romanians in Britain [PDF]

, 2018
The paper presents an analysis of everyday cosmopolitanism in constructions of Europe among young Romanian nationals living in Britain. Adopting a social representations approach, cosmopolitanism is understood as a cultural symbolic resource that is part
Billig M, Billig M, Bozatzis N, Buchowski M, Burrell K, Calhoun C, Caroline Howarth, Eleni Andreouli, Fox JE, Goffman E, Harvey D, Howarth C, McDowell L, Meleady R, Moscovici S, Neumann IB, Noble G, Nowicka M, Rabikowska M, Recchi E, Robbins B, Ryan L, Said E, Savage M, Sklair L, Stenning A, Tileaga C, Todorova M, Wessendorf S, Wessendorf S, Wolff L   +30 more
core   +2 more sources