Results 61 to 70 of about 15,150 (259)

Materialese as Border Thinking: The Multimodal Voice of Bilingual Learning Materials

Voces y Silencios: Revista Latinoamericana de Educación, 2019
This paper discusses the emerging and multidimensional category in a study about the development of a didactic material for Spanish learning in bilingual and multimodal settings. Since didactic materials for L2 education seemed to rely on geopolitics of
Yeraldine Aldana
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

TERRITORIAL THINKING AND THE LEGAL FRAMEWORK IN CROSSBORDER COOPERATION: THE RECENT SITUATION AND FIELDWORK RESULTS IN THE WESTERN ALPS

European Journal of Geography, 2013
In this article we discuss the following questions: what is the key to cross-border cooperation, particularly in the case of European mountain regions? Does the legal framework represent a starting point for the development of cross-border relations or ...
Lauranne JACOB, André SUCHET
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Schengen in the suction of sovereignism

Culture, Practice & Europeanization
This article examines how the Schengen system generates new tensions between European integration and state sovereignty. Schengen challenges the traditional concept of sovereignty by transferring border control to the European level, while simultaneously
Georg Vobruba
doaj   +1 more source

Contested externalisation: responses to global inequalities

Comparative Migration Studies, 2019
What is new about contemporary remote control across borders? An important element is the reference to human rights norms by various political actors such as NGOs, migrant associations but also national governments, international organisations and an ...
Thomas Faist
doaj   +1 more source

The dynamics of regional economic integration : a system dynamics analysis of pathways to the development of value chains in the South African Customs Union

South African Journal of Industrial Engineering, 2017
Despite progress towards improved cooperation within the Southern African Customs Union (SACU), it can be argued that real economic integration is still lacking.
Grobbelaar, S. S., Meyer, I. A.
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

La frontière : contrainte ou ressource pour l’individu ? Le « pari romantique » des pionniers de la Société des missions évangéliques de Paris, de « l’humanisation » à « l’humanitarisation » des Sotho

Les Cahiers de Framespa, 2012
The paper suggests thinking about the imaginary, imagined and true border, from the case of protestant missionaries from XIXth century and Sotho of Southern Africa.
Laurence Espinosa
doaj   +1 more source