Results 61 to 70 of about 1,568,330 (293)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Überlegungen zu einer komplexitätsorientierten Grenzforschung [PDF]

Im neuen BorderObs-Blogeintrag „Überlegungen für eine komplexitätsorientierte Grenzforschung” diskutiert Christian Wille (Universität Luxemburg) das Verhältnis von Komplexitätsdenken und Grenzforschung.
WILLE, Christian
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The potential of collaborative online international learning as a border thinking third space for global citizenship education

International Journal of Development Education and Global Learning
In this article, we examine the potential of collaborative online international learning as a borderland third space for global citizenship education.
doaj   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Border thinking and the modern Plaasroman: a study of three novels [PDF]

, 2021
In Afrikaans literature, the farm concept has a history of entanglement with ideals that are racist and nationalist. The early plaasroman (farm novel in Afrikaans) subgenre was a product of the 1920s and the 1930s, a period when Afrikaner nationalism was
Winfield, Matthew
core   +1 more source

An ex post facto study of critical thinking skills in mathematics learning based on school geography

Al-Jabar
Background: Educational disparities in Indonesia necessitate a comprehensive evaluation of students' critical thinking skills across various geographical regions, including highlands, border areas, and lowlands, to address potential educational ...
Iik Nurhikmayati, Nanang Priatna, Jarnawi Afgani Dahlan, Sona Minasyan   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Civic learning through utopian thinking on border and migration regimes. An intersectional perspective

Zeitschrift für Weiterbildungsforschung - Report
Global border and migration regimes are marked by injustices and deaths. One possibility to address these fault lines through civic adult education is by utopian thinking, the effects of which have hardly been researched empirically.
Brigitte Kukovetz
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source