Results 51 to 60 of about 15,150 (259)

The potential of collaborative online international learning as a border thinking third space for global citizenship education

open access: yesInternational Journal of Development Education and Global Learning
In this article, we examine the potential of collaborative online international learning as a borderland third space for global citizenship education.
doaj   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Frontline mobilisation as border thinking: redefining just transitions through decolonial praxis and community organising

open access: yesGlobal Social Challenges Journal
I analyse the coming together of frontline actors, particularly people of colour in the US, building on the concept of ‘just transitions’ to help solve the climate crisis as ‘border thinking or border epistemology’ within decolonial thought.
Cleovi C. Mosuela
doaj   +1 more source

Reimagining the liminal Cerrado: the virtual ancestral future

open access: yesEcology and Society
This paper examines transformations in social-ecological system through the process-relational perspective (PRP), using the concepts of the “real-possible,” the existing reality, and the “actual-virtual” potentials that exist beyond current hegemonic ...
Taís Sonetti-González   +3 more
doaj   +1 more source

Teorie (mexicko‑americké) hranice: Mestické vědomí Glorie Anzaldúy [PDF]

open access: yesGender a Výzkum, 2012
Border theory, an interdisciplinary approach to the analysis of cultures located (especially) on the U.S.-Mexican border, was to a great extent initiated by the publication of Gloria Anzaldúa’s multigenre masterpiece Borderlands/La Frontera – The New ...
Tereza Jiroutová Kynčlová
doaj  

Stereotypical Representations of the Border Space in some Mexican Fictions about Tijuana

open access: yesCatedral Tomada: Revista de Crítica Literaria Latinoamericana, 2019
The city of Tijuana, the quintessential archetype for thinking the social and cultural dynamics of life on the border, has been described and represented to the point of exhaustion in literature.
Felipe Oliver
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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