Results 51 to 60 of about 15,150 (259)
In this article, we examine the potential of collaborative online international learning as a borderland third space for global citizenship education.
doaj +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
I analyse the coming together of frontline actors, particularly people of colour in the US, building on the concept of ‘just transitions’ to help solve the climate crisis as ‘border thinking or border epistemology’ within decolonial thought.
Cleovi C. Mosuela
doaj +1 more source
Reimagining the liminal Cerrado: the virtual ancestral future
This paper examines transformations in social-ecological system through the process-relational perspective (PRP), using the concepts of the “real-possible,” the existing reality, and the “actual-virtual” potentials that exist beyond current hegemonic ...
Taís Sonetti-González +3 more
doaj +1 more source
Teorie (mexicko‑americké) hranice: Mestické vědomí Glorie Anzaldúy [PDF]
Border theory, an interdisciplinary approach to the analysis of cultures located (especially) on the U.S.-Mexican border, was to a great extent initiated by the publication of Gloria Anzaldúa’s multigenre masterpiece Borderlands/La Frontera – The New ...
Tereza Jiroutová Kynčlová
doaj
Stereotypical Representations of the Border Space in some Mexican Fictions about Tijuana
The city of Tijuana, the quintessential archetype for thinking the social and cultural dynamics of life on the border, has been described and represented to the point of exhaustion in literature.
Felipe Oliver
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

