Results 81 to 90 of about 447,397 (301)

Progressing Issues of Social Importance Through the Work of Indigenous Artists: A Social Impact Evaluation of the Native Arts and Cultures Foundation's Pilot Community Inspiration Program [PDF]

, 2017
In 2014, the Native Arts and Cultures Foundation (NACF) launched a new initiative, the Community Inspiration Program (CIP), which is rooted in the understanding that arts and cultures projects have an important role to play in motivating community ...
Miriam Jorgensen, Miskodagaaginkwe Beaudrie   +1 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Schengen in the suction of sovereignism

Culture, Practice & Europeanization
This article examines how the Schengen system generates new tensions between European integration and state sovereignty. Schengen challenges the traditional concept of sovereignty by transferring border control to the European level, while simultaneously
Georg Vobruba
doaj   +1 more source

Contested externalisation: responses to global inequalities

Comparative Migration Studies, 2019
What is new about contemporary remote control across borders? An important element is the reference to human rights norms by various political actors such as NGOs, migrant associations but also national governments, international organisations and an ...
Thomas Faist
doaj   +1 more source

The dynamics of regional economic integration : a system dynamics analysis of pathways to the development of value chains in the South African Customs Union

South African Journal of Industrial Engineering, 2017
Despite progress towards improved cooperation within the Southern African Customs Union (SACU), it can be argued that real economic integration is still lacking.
Grobbelaar, S. S., Meyer, I. A.
doaj   +1 more source

NH Congressional Races Remain Close 10/03/2012 [PDF]

, 2012
Democrats Carol Shea-Porter and Ann McLane Kuster have pulled ahead of incumbent Republicans Frank Guinta and Charlie Bass in races for New Hampshire’s two Congressional seats but both races are within the poll’s margin of sampling error.
Survey Center, UNH
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

La frontière : contrainte ou ressource pour l’individu ? Le « pari romantique » des pionniers de la Société des missions évangéliques de Paris, de « l’humanisation » à « l’humanitarisation » des Sotho

Les Cahiers de Framespa, 2012
The paper suggests thinking about the imaginary, imagined and true border, from the case of protestant missionaries from XIXth century and Sotho of Southern Africa.
Laurence Espinosa
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source