Results 41 to 50 of about 231,174 (267)

Peculiarities of the first time diagnosed mental disorders formationin after the coronavirus disease COVID-19

European Psychiatry
Introduction The world community is only at the beginning of awareness of the peculiarities of the formation, course and outcome of the psychopathological consequences of the impact of the SARS-CoV-2 pandemic. Objectives To investigate the clinical and
N. O. Maruta, V. Y. Fedchenko, T. V. Panko, I. O. Yavdak   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The Cross-Sectional and Longitudinal Associations between Household Chaos, Perceived Stress, and Borderline Personality Disorder Features in Outpatient Youth

Youth
This study examined how household chaos, perceived stress, and their interaction are related to borderline personality disorder (BPD) features both cross-sectionally and at 1-year follow-up in outpatient youth. Data from 143 youth were analysed.
Anouk Aleva, Geerte de Boois, Christel J. Hessels, Odilia M. Laceulle   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Role of CD10 Immunoexpression in Grading Phyllodes Tumour of the Breast [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Fibroepithelial tumours are a heterogeneous group of biphasic neoplasms consisting of a proliferation of both epithelial and stromal components. Fibroadenoma (FA) and Phyllodes Tumour (PT) constitute the major entities. It is crucial to
Maithili Mandar Kulkarni, Siddhi Gaurish Sinai Khandeparkar, Avinash R Joshi, Vishakha Kothikar, Anuja Nasare, Sukhada Patil, Supriya Niraspatil, Bhagyashree Dhande   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Neural Correlates of Social Inclusion in Borderline Personality Disorder

Frontiers in Psychiatry, 2018
Humans engage in social interactions and have a fundamental need and motivation to establish and maintain social connections. Neuroimaging studies particularly focused on the neural substrates of social exclusion in healthy subjects (HC), borderline ...
Kathrin Malejko, Dominik Neff, Rebecca Brown, Paul L. Plener, Martina Bonenberger, Birgit Abler, Heiko Graf   +6 more
doaj   +1 more source

Factors Associated With People’s Accessibility to Mental Healthcare Services in Ukraine: Focusing on Household Head Vulnerability

International Journal of Public Health, 2023
Objectives: This study examines the factors associated with access to mental healthcare services among people living in the government-controlled areas (GCAs) of Donetsk and Luhansk oblasts in Ukraine.Methods: The 2020 Ukraine Multi-Sector Needs ...
Min-Hee Heo, Eun-Mi Song, Hui-Won Jeon, Kyoung-Beom Kim, Jin-Won Noh   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Borderline empathy and borderline pathology: Constitutional considerations

Comprehensive Psychiatry, 1987
Abstract The authors present some data on correlations between empathy and recalled parental practices for both borderline and neurotic patients. Speculations are offered as to how this pattern of correlations provide some interesting data consistent with the possibility of a constitutional factor in the borderline syndrome.
N, Hoffman, H, Frank
openaire   +2 more sources