Results 71 to 80 of about 536,146 (300)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Clinicopathological Study of Surface Epithelial Tumours of the Ovary: An Institutional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: It is an established fact that tumours of ovary inherit a spectrum of histogenetic background, the variety being more than any other organ. Surface epithelial stromal tumours of ovary being the most common type of ovarian tumours form a
Nalini Modepalli, Suguna Belur Venugopal
doaj   +1 more source

The complexity of general-valued CSPs seen from the other side

open access: yes, 2018
The constraint satisfaction problem (CSP) is concerned with homomorphisms between two structures. For CSPs with restricted left-hand side structures, the results of Dalmau, Kolaitis, and Vardi [CP'02], Grohe [FOCS'03/JACM'07], and Atserias, Bulatov, and ...
Carbonnel, Clement   +2 more
core   +2 more sources

Theories of vagueness and theories of law [PDF]

open access: yes, 2019
It is common to think that what theory of linguistic vagueness is correct has implications for debates in philosophy of law. I disagree. I argue that the implications of particular theories of vagueness on substantive issues of legal theory and practice ...
Silk, Alex
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Poetas en la frontera de México-Estados Unidos de América: Heriberto Yépez y Esther M. García

open access: yesLiteratura Mexicana, 2019
La poesía mexicana se caracteriza en los últimos años por la descentralización de algunas prácticas literarias que tienen que ver con el conflicto producido en la frontera de México-eua.
Ignacio Ballester Pardo
doaj   +1 more source

Revisão e verificação das propriedades psicométricas da dimensão instabilidade de humor do inventário dimensional clínico da personalidade [PDF]

open access: yes, 2015
El presente estudio tuvo como objetivo examinar la dimensión Inestabilidad del Humor del Inventario Dimensional Clínico de la Personalidad (IDCP), y la investigación de sus propiedades psicométricas.
De-Francisco Carvalho, Lucas   +1 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

In Silico Approach to Molecular Profiling of the Transition from Ovarian Epithelial Cells to Low-Grade Serous Ovarian Tumors for Targeted Therapeutic Insights

open access: yesCurrent Issues in Molecular Biology
This paper aims to elucidate the differentially coexpressed genes, their potential mechanisms, and possible drug targets in low-grade invasive serous ovarian carcinoma (LGSC) in terms of the biologic continuity of normal, borderline, and malignant LGSC ...
Asim Leblebici   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy