Results 151 to 160 of about 64,820 (254)

Ovarian borderline tumor presenting as ovarian torsion in a 17-year-old patient: a case report. [PDF]

open access: yesJ Med Case Rep, 2021
Vicente AP   +3 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

open access: yesAdvanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels   +2 more
wiley   +1 more source

A Rare Case of Ovarian Serous Borderline Tumor Recurrence with Muscle Metastasis. [PDF]

open access: yesAm J Case Rep
Yamamura A   +10 more
europepmc   +1 more source

Paratesticular Serous Borderline Tumor in a Pediatric Patient. [PDF]

open access: yesCase Rep Pathol, 2020
Meza IAO   +5 more
europepmc   +1 more source

Clear cell borderline tumor without fibromatous component: Pathological and literature review and report of two cases. [PDF]

open access: yesMol Clin Oncol, 2021
Hada T   +9 more
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Laparoscopic treatment of a rare primary peritoneal serous borderline tumor: Case report and narrative review of the literature. [PDF]

open access: yesGynecol Oncol Rep
Iannone V   +9 more
europepmc   +1 more source

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