Results 171 to 180 of about 378,681 (299)

A national border-based assessment of Malawi’s transboundary aquifer units: Towards achieving sustainable development goal 6.5.2

, 2020
Christina Fraser, Robert M. Kalin, Modesta Kanjaye, Zione Uka   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Establishing a nurturing micro-sleep environment may positively influence children's overall development. [PDF]

Sleep Med X
Bruni O.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Unusual White Plaques on the Tongue in a 37-Year-Old Male. [PDF]

Clin Case Rep
García Iglesias JR, Diz-Dios P, Limeres-Posse J, Diniz-Freitas M.   +3 more
europepmc   +1 more source

The historical trends of brazilian development and its relations with rural socio-spatial development : the case of the northwest border of Rio Grande do Sul

, 2018
José Phelippe Jorge de Sousa Machado, Eduardo Ernesto Filippi   +1 more
openalex   +1 more source

Corpo, dados, presença e tecnologia em Border, do Rhizomatiks

Luiza Marcato Camargo de Sousa, Fausto Viana   +1 more
openalex   +2 more sources

Zmiany w użytkowaniu gruntów oraz gęstość zabudowy na styku miasto–obszar wiejski jako przejawy suburbanizacji Nowego Sącza / Changes in land use and the housing density on the city–rural area border as a result of the suburbanization processes of Nowy Sącz [PDF]

, 2017
Piotr Serafin
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Changes in Choroidal Structure Associated with Idiopathic Macular Hole Border Morphology. [PDF]

J Clin Med
Endo H, Terasaki H, Sonoda S, Ito Y, Katsuta S, Kase S.   +5 more
europepmc   +1 more source