Results 41 to 50 of about 244,820 (268)

Use of Treatment Escalation Plans to Guide Care Planning on a Specialist Dementia Unit

open access: yesBJPsych Open
Aims This audit reviewed the use of Treatment Escalation Plans (TEPs) on the Borders Specialist Dementia Unit (BSDU). We aimed to use data on completion rates and quality to adapt the TEP form to both improve practice and develop a more specialised form
Charlotte Russell, Lucy Calvert
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Improving Delegation of New Patient Referral Allocations to Manage the Workload Burden of Staff

open access: yesBJPsych Open
Aims: Referrals to Old Age Community Mental Health Team (CMHT OP) Guildford/Waverley have increased in number and workload. The purpose was to see the number of referrals received and how to improve the referral allocation practice concerning delegation
Siyament Sacaklidir   +2 more
doaj   +1 more source

Transforming care for people with dementia using the Internet of Things

open access: yesInternational Journal of Integrated Care, 2019
There are currently around 46.8 million people living with dementia around the world and this number is estimated to increase to 74.7 million by 2030 and to 131.5 million by 2050.
Ramin Nilforooshan   +6 more
doaj   +1 more source

The use of artificial intelligence and machine learning in the care of people with dementia: A literature review

open access: yesEuropean Psychiatry, 2021
Introduction Artificial intelligence and machine learning are increasingly being researched within the field of psychiatry to find out what use it might be.
G. Belam, R. Nilforooshan
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Suspected Case of Kluver-Bucy Syndrome in an Adolescent Male Following SARS-CoV-2 Infection

open access: yesBJPsych Open
Aims We present a case of suspected Kluver-Bucy syndrome in an adolescent male, following a SARS-CoV-2 (Covid-19) infection. To the best of our knowledge, KBS has not been associated with Covid-19 before. Methods A 15-year-old male with a background of
Christina Barmpagianni   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Improving Physical Health Monitoring on a Working-Age General Adult Inpatient Ward: A Quality Improvement Project

open access: yesBJPsych Open
Aims: Individuals with severe mental illness (SMI) face a significantly reduced life expectancy, primarily due to preventable physical health conditions.
Mohsin Nazeer Muhammed   +2 more
doaj   +1 more source

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