Results 61 to 70 of about 244,820 (268)
Ethics and Economics of the COVID-19 Pandemic in the United States
Health Services Research & Managerial Epidemiology, 2020 The Covid-19 experience provides a natural experiment in personal and social ethics. Difficult decisions are routinely made to optimize lives and livelihoods.
Peter Hilsenrath, Tyrone Borders
doaj +1 more source
Bordering Migration/Migrating Borders
, 2019 From the Great Wall of China to the Berlin Wall, border walls have long served as symbols of visible, fortified manifestations of sovereign control. Increasingly, however, prosperous countries utilize sophisticated legal tools to restrict mobility by detaching the border and its migration control functions from a fixed territorial marker, creating a ...
openaire +2 more sources
Borders, Bordering, and the Transnation
English Academy Review, 2019 The hope for a better life that drives increasing numbers of refugees to seek shelter has corresponded to an increasingly hysterical sealing of national borders around the world.
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
F1000ResearchBackground Dietary behaviours influence obesity and chronic disease. In Saudi Arabia, Westernised diets and sedentary lifestyles have driven rising obesity. This study explores generational dietary patterns to inform Saudi Vision 2030 planning. Methods A
Jenan Alanazi +4 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Journal of Primary Care & Community HealthIntroduction: Rural cancer survivors often face greater barriers to treatment, which may translate into worse satisfaction with health care. Objective: To examine rural versus urban differences in satisfaction with health care among Medicare cancer ...
Tyrone F. Borders
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Designing text-messaging (SMS) in HIV programs: ethics-framed recommendations from the field
The Pan African Medical Journal, 2015 Text messages (SMS) are being increasingly integrated into HIV programs across Southern Africa to improve patient adherence, linkage to care and provide psycho-social support.
Guillermo Marténez Pérez +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source