Bordetella holmesii: initial genomic analysis of an emerging opportunist [PDF]
Bordetella holmesii is an emerging opportunistic pathogen that causes respiratory disease in healthy individuals and invasive infections among patients lacking splenic function. We used 16S rRNA gene analysis to confirm B. holmesii as the cause of bacteremia in a child with sickle cell disease.
Saul Hymes, , Paul Planet
exaly +5 more sources
Bordetella holmesii bacteremia in sickle cell disease [PDF]
AbstractPatients with sickle cell disease (SCD) have an increased risk of invasive bacterial infection because of hyposplenism. Bordetella holmesii is a recently described Gram‐negative coccobacillus with an apparent predilection for asplenic hosts. We report two patients with SCD and B. holmesii bacteremia. Fastidious growth in culture and a typically
Charles T Quinn
exaly +5 more sources
Comparison of Bordetella species identification among differing rt-PCR assays in the United States [PDF]
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole +7 more
doaj +2 more sources
Positivity analysis of Bordetella spp. and SARS-CoV-2 coinfections in clinical samples from Colombia, 2021–2022 [PDF]
Pertussis and COVID-19 are respiratory diseases with similar clinical manifestations, complicating diagnosis. In Colombia, pertussis surveillance is based on probable cases confirmed through laboratory detection of Bordetella pertussis.
Valentina Bonilla-Bravo +11 more
doaj +2 more sources
Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species [PDF]
Acellular pertussis vaccines protect against severe pertussis, but vaccine-induced immunity wanes over time. Prior animal studies showed that T-cell responses are integral to long-lasting immunity.
Muktha S. Natrajan +9 more
doaj +2 more sources
Prosthetic-Joint-Associated Bordetella holmesii Infection. [PDF]
Abstract Bordetella holmesii is a globally distributed pathogen that is increasingly recognized as a cause of both pertussis-like respiratory infections and invasive disease. In this study, we describe a case of an immunocompetent man who developed B holmesii infection of his femoral prosthesis—the fifth B holmesii orthopedic infection ...
Humphrey JM +9 more
europepmc +4 more sources
Recurrent Bordetella holmesii Bacteremia and Nasal Carriage in a Patient Receiving Rituximab [PDF]
Liem Binh Luong Nguyen +7 more
doaj +2 more sources
Bordetella holmesii, an emerging cause of septic arthritis. [PDF]
ABSTRACT Bordetella holmesii is a well-described pathogen in asplenic and immunocompromised patients. Here we report the first two published cases of septic arthritis caused by B. holmesii documented in apparently immunocompetent patients and unaccompanied by bacteremia.
Abouanaser SF +8 more
europepmc +4 more sources
Whole-Genome Sequences of Bacteremia Isolates of Bordetella holmesii. [PDF]
ABSTRACT Bordetella holmesii causes respiratory and invasive diseases in humans, but its pathogenesis remains poorly understood. We report here the genome sequences of seven bacteremia isolates of B. holmesii , including the type strain.
Tettelin H +7 more
europepmc +4 more sources
Bordetella holmesii: Lipid A Structures and Corresponding Genomic Sequences Comparison in Three Clinical Isolates and the Reference Strain ATCC 51541 [PDF]
Valerie Bouchez +2 more
exaly +2 more sources

