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Bordetella pertussis(Pertussis)
Pediatrics in Review, 20181. Heather L. Daniels, DO* 2. Camille Sabella, MD* 1. *Center for Pediatric Infectious Diseases, Cleveland Clinic Children’s, Cleveland, OH * Abbreviations: CDC: : Centers for Disease Control and Prevention DTaP: : diphtheria, tetanus, and acellular pertussis vaccine DTwP: : diphtheria, tetanus, and whole cell ...
Heather L, Daniels, Camille, Sabella
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Pertussis toxin (Bordetella pertussis)
1997Abstract PT (Sekura et al. 1985) is a protein of 105 000 daltons composed of five noncovalently linked subunits named 51 through 55, and organized into two functional domains called A and B (Tamura et al. 1982). The A domain, which is composed of the 51 subunit, is an enzyme that intoxicates eukaryotic cells by ADP-ribosylating their GTP¬
R Rappuoli, M G Pizza
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Serotyping Bordetella pertussis strains
Vaccine, 1989The serotyping scheme for Bordetella pertussis, developed in the 1950s, depends on the presence or absence of various strains of three major agglutinogens, two of which have been shown to be fimbrial proteins, and several minor agglutinogens, the biochemical nature of which is unknown.
A, Robinson, L A, Ashworth, L I, Irons
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Surface Proteins of Bordetella pertussis
Clinical Infectious Diseases, 1988Bordetella pertussis cells express multiple virulence-associated surface proteins, including adenylate cyclase, agglutinogens 2 and 3, filamentous hemagglutinin, pertussis toxin, and outer-membrane protein (Omp) 30/32 and Omp91. Surface proteins that are not virulence-associated include three peptidoglycan-associated Omps of apparent molecular weights ...
C D, Parker, S K, Armstrong
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2020
Bordetella pertussis is the causative agent of pertussis or whooping cough, a serious disease of the respiratory tract. B. pertussis strains produce two serologically distinct fimbriae that were first identified as agglutinogens, i.e., antigens that induce the production of antibodies that agglutinate the bacteria.
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Bordetella pertussis is the causative agent of pertussis or whooping cough, a serious disease of the respiratory tract. B. pertussis strains produce two serologically distinct fimbriae that were first identified as agglutinogens, i.e., antigens that induce the production of antibodies that agglutinate the bacteria.
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Surface Antigens of Bordetella Pertussis
1985Bordetella pertussis and other Bordetella species cause respiratory infections in humans and in a variety of animals. Clinical isolates of B. pertussis have multiple virulence factors, several of which have been reported to induce protective immunity.
C D, Parker, S K, Armstrong, D W, Frank
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Virulence factors of Bordetella pertussis
Antonie van Leeuwenhoek, 1988Clearly, B. pertussis has evolved very elaborate mechanisms to maintain itself in the human host. Three different proteins (FHA, pertussis toxin and fimbriae) have been implicated in adherence. Furthermore, a number of toxins are produced (pertussis toxin, adenylate cyclase, dermonecrotic toxin, and tracheal cytotoxin) which destroy the clearance ...
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