Results 21 to 30 of about 506,369 (146)

Site‐Specific Labeling of RNAs with Modified and 19F‐Labeled Nucleotides by Chemo‐Enzymatic Synthesis

open access: yesChemistry – A European Journal, Volume 29, Issue 25, May 2, 2023., 2023
A library of post‐transcriptional modifications and synthetic modified nucleosides for the site‐specific alteration of RNAs applying a chemo‐enzymatic method is presented. This method overcomes the limitations of other established and well‐known RNA synthesis techniques.
Alexey Sudakov   +5 more
wiley   +1 more source

Boris Hessen and Newton's God [PDF]

open access: yes, 2019
A significant thread in Boris Hessen‟s iconic essay, The Social and Economic Roots of Newton’s Principia (1931), is his critique of Newton‟s involving God in his physics.
Trisokkas, Ioannis
core   +3 more sources

Das COVID19‐NMR‐Konsortium: Ein öffentlicher Bericht über den Einfluss dieser neuen globalen Kollaboration

open access: yesAngewandte Chemie, Volume 135, Issue 14, March 27, 2023., 2023
Dieser Viewpoint Article beschreibt die Selbstorganisation der weltweiten NMR‐Gemeinschaft, um einen zeitnahen Beitrag zur Bekämpfung von SARS‐CoV‐2 zu leisten. Diese neue Art der kollaborativen Forschung könnte als Modell für die Bewältigung weiterer aktueller und künftiger großer gesellschaftlicher Bedürfnisse dienen, ohne dabei mit ...
Elke Duchardt‐Ferner   +10 more
wiley   +1 more source

The COVID19‐NMR Consortium: A Public Report on the Impact of this New Global Collaboration

open access: yesAngewandte Chemie International Edition, Volume 62, Issue 14, March 27, 2023., 2023
This Viewpoint Article discusses how the global NMR community organized itself to rapidly contribute to combat SARS‐CoV‐2. This new collaborative research might serve as model for future ways to address great societal needs, without competing with curiosity‐driven research.
Elke Duchardt‐Ferner   +10 more
wiley   +1 more source

EETTlib—Energy‐efficient train timetabling library

open access: yesNetworks, Volume 81, Issue 1, Page 51-74, January 2023., 2023
Abstract We introduce EETTlib, an instance library for the Energy‐Efficient Train Timetabling problem. The task in this problem is to adjust a given timetable draft such that the energy consumption of the resulting railway traffic is minimized. To this end, the departure times of the trains can be slightly, and their velocity profiles on each trip can ...
Andreas Bärmann   +4 more
wiley   +1 more source

Astrocyte‐targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis

open access: yesGlia, Volume 70, Issue 5, Page 842-857, May 2022., 2022
Main Points Astrocytes are effective target cells for gene therapy against amyotrophic lateral sclerosis. SOD1‐targeting gene therapy in astrocytes protects fast‐fatigable motor units. RNAi gene therapy directed to astrocytes induces motoneuron plasticity.
Cylia Rochat   +7 more
wiley   +1 more source

The Social Study of Science: The Resurgence of Historical Materialism

open access: yesEncyclopedia
The Social Study of Science (SSS) constitutes an interdisciplinary domain dedicated to examining the profound influence of social, political, and cultural factors on the development of scientific research and practice. Rejecting conceptions of science as
Constantine (Kostas) Skordoulis
doaj   +1 more source

Die Hessen als Reichstagswähler. 3. Band: Großherzogtum/Volksstaat Hessen 1867-1933

open access: yes, 2020
Elektronische Reproduktion von: Die Hessen als Reichstagswähler : Tabellenwerk zur politischen Landesgeschichte 1867 - 1933 / von Thomas Klein. 3. Band: Großherzogtum/Volksstaat Hessen, 1867 - 1933. - Marburg : Elwert, 1995.
Klein, Thomas
core   +1 more source

Strong gradients, cool performance: A 64‐channel array coil with concurrent field monitoring and thermal control for ex vivo diffusion‐weighted brain imaging using the 3T connectome 2.0 MRI scanner

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 5, Page 2268-2285, November 2025.
Abstract Purpose High‐resolution ex vivo diffusion‐weighted imaging (dMRI) with high b$$ b $$‐values presents significant challenges, including low signal‐to‐noise ratio (SNR), magnetic field perturbations, and temperature‐related measurement shifts.
Alina Müller   +14 more
wiley   +1 more source

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