Results 141 to 150 of about 932 (230)

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Trimethylaluminum Activates Zeolite-Confined Lanthanum Borohydrides to Enhance Catalytic C-H Borylation. [PDF]

J Am Chem Soc
Li Y, Kobayashi T, Meira DM, An L, Qi L, Sadow AD.   +5 more
europepmc   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Theoretical prediction of nanosizing effects and role of additives in the decomposition of Mg(BH₄)₂. [PDF]

RSC Adv
Pantaleone S, Albanese E, Donà L, Corno M, Baricco M, Civalleri B.   +5 more
europepmc   +1 more source

Synthesis, Polymorphism and Thermal Decomposition Process of (n-C₄H₉)₄NRE(BH₄)₄ for RE = Ho, Tm and Yb. [PDF]

Materials (Basel), 2021
Wegner W, Jaroń T.
europepmc   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

Hydrogen production from NaBH₄ hydrolysis over chemically reduced TiO₂-based Ru nanocomposites and their antimicrobial performance. [PDF]

Sci Rep
Halvacı E, Mutlag F, Elaibi H, Sen F.
europepmc   +1 more source

Thermodynamic Mechanisms of Co‐S Bond Anchoring in Few‐Layered 1T‐MoS2 for Enhanced Capacitive Performance via Spin State Regulation and Ion Diffusion Kinetics

ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 4, July 2026.
The one‐pot hydrothermal prep of Co‐doped few‐layer 1T‐MoS2 shows Co‐S bonds stabilizing the 1T phase, enhancing supercapacitor performance. Few‐layered 1T‐MoS2 is highly promising for supercapacitor applications due to its wide interlayer spacing, high electrical conductivity, and abundant active sites.
Qingling Jia, Han Li, Shun Lu, Chuanyin Xiong, Yongxing Zhang   +4 more
wiley   +1 more source

Synthesis, Characterization, Antioxidant Evaluation, Cytotoxicity Studies, and Molecular Docking of Novel Sulfonamide Derivatives

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
A series of novel sulfonamide derivatives (4a–i) were synthesized and characterized. Compound 4d showed significant antioxidant activity, while compounds 4g, 4h, and 4i exhibited high cytotoxicity against ovarian and prostate cancer cells, particularly 4h with a log IC50 of 1.343 µg/mL.
Ouissal Bouraoui, Güldeniz Şekerci, Khaled Mesbah, James A. Ezugwu, Rachid Benkiniouar, Suat Tekin, Fatümetüzzehra Küçükbay, Houssem Boulebd, Hasan Küçükbay   +8 more
wiley   +1 more source

Photocatalytic Transfer Hydrogenation Using Plastic Hydrolysates as Hydrogen Donor

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Plastic waste is transformed into functional amines via solar‐driven transfer hydrogenation. Soluble monomers from acid hydrolysis of waste polymers serve as a hydrogen (electron/proton)donors in the selective reduction of nitroarenes using a visible light active photocatalyst consisting of cobalt promoted molybdenum disulfide integrated in cyanamide ...
Papa K. Kwarteng, Afreen H. Naceruddin, Erwin Reisner   +2 more
wiley   +2 more sources