Results 151 to 160 of about 3,734 (241)

Traces of Elements in the Electrochemical Reductive Amination of Acetone: Uncovering Bi as Substitute for Pb

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 13, 23 March 2026.
This study investigates the impact of various p‐block element impurities in the electrochemical reductive amination and reveals with Bi a less toxic alternative for Pb. The utilization of Bi as additive was further optimized by studying the impact of additive concentration, reaction temperature, and cathode material on amine yield, offering new ...
Justus Kümper   +5 more
wiley   +1 more source

Synthesis and Biological Profile of Substituted Pyrrolidinyl Carboxamides for Acyl‐ACP Thioesterase Inhibition

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 12, 23 March 2026.
The work outlined herein covers a series of novel herbicidal lead structures that possess a pyrrolidinyl pyrazole carboxamide scaffold as a key structural feature, carrying further substituted benzyl side chains. Based on scaffold hopping approaches from known fungicidal and herbicidal compounds and utilizing an optimized synthetic approach, a broader ...
Elisabeth Asmus   +24 more
wiley   +1 more source

Synthesis of Heterocyclic Scaffolds from Nitrobenzyl Alcohols Using Reduction‐Generated Azaquinone Methides and Cyclization

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 12, 23 March 2026.
Intramolecular cyclization to quench an in situ reduction‐generated azaquinone methide is a strategy that could be used for late‐stage heterocycle synthesis. Herein, synthetically accessible 4‐nitrobenzyl alcohols with a nucleophilic handle adjacent to the benzyl alcohol group are reduced under mild conditions to afford six‐ and seven‐membered ...
Harrison M. Lewin   +4 more
wiley   +1 more source

Synthesis of Niraparib via Chemoenzymatic Dearomatization of Substituted Pyridines

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
The synthesis of the PARP inhibitor Niraparib has been achieved via a chemoenzymatic dearomatization strategy. Chemical reduction combined with a one‐pot enzymatic cascade comprising an amine oxidase (AmOx) and an ene imine reductase (EneIRED) allowed for asymmetric reduction with high enantioselectivity.
Tabea Gerlach   +3 more
wiley   +1 more source

Combustion Resistant Borohydrides and Their Chemical Interactions with Li-Metal Surfaces: An Experimental and Theoretical Study. [PDF]

open access: yesACS Cent Sci
Tomich AW   +10 more
europepmc   +1 more source

Metal Borohydrides beyond Groups I and II: A Review. [PDF]

open access: yesMaterials (Basel), 2021
Suárez-Alcántara K, Tena García JR.
europepmc   +1 more source

An Efficient PdPt/rGO Catalyst for Hydrogen Electrolysis in Acidic Medium: Structure‐Activity Relationships and CO‐Tolerance

open access: yesChemElectroChem, Volume 13, Issue 6, 17 March 2026.
PdPt alloys supported on reduced graphene oxide exhibit enhanced hydrogen oxidation and evolution activity in acidic media. Minimal Pt incorporation into Pd tunes the d‐band center and weakens hydrogen and CO binding, delivering superior activity and CO tolerance.
Shwetambara Jha   +5 more
wiley   +1 more source

Electrochemical Decarboxylative Hydroxylation for the Sustainable Synthesis of Bempedoic Acid

open access: yesChemElectroChem, Volume 13, Issue 6, 17 March 2026.
A sustainable synthesis of bempedoic acid is achieved using electrochemical hydroxylative decarboxylation as the key step. Starting from Meldrum's acid, mild metal‐free alkylation, hydrolysis, and decarboxylation provide the key precursor, which is electrochemically converted to the alcohol intermediate and then hydrolyzed to the final product ...
Pietro Ronco   +6 more
wiley   +1 more source

Chemical Bonds Containing Hydrogen: Choices for Hydrogen Carriers and Catalysts. [PDF]

open access: yesAngew Chem Int Ed Engl
Cashel J   +9 more
europepmc   +1 more source

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