Results 101 to 110 of about 8,945,775 (339)
Advanced Materials, EarlyView.The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj +8 more
wiley +1 more source
Sub-Picomolar Inhibition of HIV-1 Protease with a Boronic Acid
Journal of the American Chemical Society, 2018 Boronic acids have been typecast as moieties for covalent complexation and are employed only rarely as agents for noncovalent recognition. By exploiting the profuse ability of a boronic acid group to form hydrogen bonds, we have developed an inhibitor of
I. Windsor +5 more
semanticscholar +1 more source
Tuning the Dynamics of Boronic Acid Hydrazones and Oximes with pH and Redox Control [PDF]
, 2020 The reaction between acyl hydrazide and methylhydroxylamine with 2-formylphenylboronic acid (2-FPBA) are measured in aqueous buffer at concentrations appropriate for bioconjuagtion (0.1 mM).
Dylan, Domaille, Gun Su, Han
core +2 more sources
“Smelltronics”—From Gas to Smell Sensing
Advanced Materials, EarlyView.The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono +7 more
wiley +1 more source
Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center
Biochemistry, 2020 Boronic acids have been successfully employed as inhibitors of hydrolytic enzymes. Typically, an enzymatic nucleophile catalyzing hydrolysis adds to the electrophilic boron atom forming a tetrahedral species that mimics the intermediate(s)/transition state(s) for the hydrolysis reaction.
Amar Nath Sharma +4 more
openaire +3 more sources
Advanced Materials, EarlyView.Water harvesting, radiative cooling, and interfacial solar evaporation are fundamentally governed by coupled heat, mass, and light transport processes. These processes are mediated by pore architecture, including pore size, connectivity, and hierarchical organization.
Dejan J. Trajkovski +5 more
wiley +1 more source
Molecules, 2019 Histone acetylation and deacetylation play an essential role in the epigenetic regulation of gene expression. Histone deacetylases (HDAC) are a group of zinc-binding metalloenzymes that catalyze the removal of acetyl moieties from lysine residues from ...
Gnanendra Shanmugam +2 more
doaj +1 more source
Radiative Thermal Management for Extreme Environments: Mechanisms and Design Strategies
Advanced Materials, EarlyView.In this review, we discuss the fundamental mechanisms of radiative cooling and solar heating, material and structural design strategies, hybrid approaches integrating additional heat transfer pathways, and durability‐oriented designs addressing environmental stresses.
Hyung Rae Kim +5 more
wiley +1 more source
Assembly of synthetic Aβ miniamyloids on polyol templates
Beilstein Journal of Organic Chemistry, 2015 Covalent dynamic chemistry is used to mimic the first steps of the highly cooperative fibril formation of Aβ peptides. For that purpose, Aβ peptide pentapeptide boronic acids 1 and 2 were synthesized by solid-phase peptide synthesis and studied in ...
Sebastian Nils Fischer, Armin Geyer
doaj +1 more source
Pharmaceutics, 2016 Boronic acids have been widely investigated for their potential use as glucose sensors in glucose responsive polymeric insulin delivery systems. Interactions between cyclic diols and boronic acids, anchored to polymeric delivery systems, may result in ...
Nabil A. Siddiqui +3 more
doaj +1 more source