Results 171 to 180 of about 8,945,775 (339)

Reductive coupling of nitro compounds with boronic acid derivatives: an overview. [PDF]

open access: yesRSC Adv, 2023
Behmagham F   +8 more
europepmc   +1 more source

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

open access: yesAdvanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo   +6 more
wiley   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

open access: yesAdvanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu   +15 more
wiley   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

open access: yesAdvanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong   +9 more
wiley   +1 more source

The boronic acid Mannich reaction in alkaloid synthesis

open access: yes, 2013
Our work on the application of the boronic acid Mannich reaction to the synthesis of pyrrolizidine alkaloids is ...
Matthew Wotherspoon (20115888)   +5 more
core  

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

open access: yesAdvanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan   +7 more
wiley   +1 more source

Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery

open access: yesAdvanced Science, EarlyView.
Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan   +13 more
wiley   +1 more source

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