Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar +2 more
wiley +1 more source
Peptidic Boronic Acid <i>Plasmodium falciparum</i> SUB1 Inhibitors with Improved Selectivity over Human Proteasome. [PDF]
Withers-Martinez C +6 more
europepmc +1 more source
Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley +1 more source
Catalyst‐controlled nitrene transfer unlocks divergent reactivity of bicyclo[1.1.0]butanes. Rhodium catalysis promotes selective strain‐release amination to access cyclobutene and cyclobutane amino‐acid scaffolds, whereas visible‐light photocatalysis redirects nitrene reactivity toward double amination and skeletal remodeling, providing a complementary
Aksar Ali +5 more
wiley +1 more source
Regioselective Aldehyde Decarbonylation through Palladium-Catalyzed Nitrile Boronic Acid Cross-Coupling. [PDF]
Paikin ZE, Talbott JM, Raj M.
europepmc +1 more source
Simple Binding and Dissociation of a Sialoglycoprotein Using Boronic Acid-Modified Functional Interfaces on Microparticles. [PDF]
Horiguchi Y +4 more
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Boronic Acid-Containing 3<i>H</i>- pyrazolo[4,3-<i>f</i>]quinoline Compounds as Dual CLK/ROCK Inhibitors with Anticancer Properties. [PDF]
Dayal N +4 more
europepmc +1 more source
Harnessing a bis-electrophilic boronic acid lynchpin for azaborolo thiazolidine (ABT) grafting in cyclic peptides. [PDF]
Das BK +6 more
europepmc +1 more source
Boronic acid-functionalized Fe3O4 nanoparticles for activity-preserved enrichment of low-abundance bacteria from real samples. [PDF]
Chen J +7 more
europepmc +1 more source
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Nickel-Catalyzed Coupling of Arynes, Alkenes, and Boronic Acids: Dual Role of the Boronic Acid†
Angewandte Chemie - International Edition, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thiruvellore Thatai Jayanth +1 more
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