Hopelessness in Patients with Early-Stage Relapsing-Remitting Multiple Sclerosis [PDF]
Susana Sainz de la Maza,1 Jorge Maurino,2 Tamara Castillo-Triviño,3 Mónica Borges,4 Berta Sebastián Torres,5 Javier Sotoca,6 Ana María Alonso Torres,7 Ana B Caminero,8 Laura Borrega,9 José L Sánchez-Menoyo,10 Francisco J Barrero-Hernández,11 Carmen ...
Sainz de la Maza S +23 more
doaj +2 more sources
Empower: Design of a digital intervention for workplace stress and mental health. A European study [PDF]
Introduction Work stress, anxiety and depression have an enormous impact on the well-being of employees, their employers, and society. Due to the loss of productivity, common mental disorders have a substantial economic impact.
C. M. Van Der Feltz-Cornelis +11 more
doaj +2 more sources
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand-binding assay [PDF]
IntroductionThe kinetics of ligand binding to G protein-coupled receptors (GPCRs) is an important optimization parameter in drug discovery. Traditional radioligand assays are labor-intensive, preventing their application at the early stages of drug ...
Leire Borrega-Roman +32 more
doaj +3 more sources
Effects of High-Intensity Interval Training and Moderate-Intensity Training on Stress, Depression, Anxiety, and Resilience in Healthy Adults During Coronavirus Disease 2019 Confinement: A Randomized Controlled Trial [PDF]
Objective: This study aimed to compare the effects of two intervention programs, (1) high-intensity interval training (HIIT) and (2) moderate-intensity training (MIT), on anxiety, depression, stress, and resilience during the confinement caused by the ...
Yolanda Borrega-Mouquinho +4 more
doaj +2 more sources
Design and development of a digital intervention for workplace stress and mental health (EMPOWER) [PDF]
Purpose: We describe the design and development of the European Platform to Promote health and wellbeing in the workplace (EMPOWER) digital intervention that provides an integrative user programme meeting the needs of employees and employers in ...
Christina M. van der Feltz-Cornelis +20 more
doaj +2 more sources
Clinical Course and Outcome of Patients with SARS-CoV-2 Alpha Variant Infection Compared to Patients with SARS-CoV-2 Wild-Type Infection Admitted to the ICU [PDF]
The alpha variant of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is associated with higher transmissibility and possibly higher mortality compared with wild-type SARS-CoV-2. However, few data are available on the clinical course
Jorge Garcia Borrega +12 more
doaj +2 more sources
Multidimensional Regional Development in EU: A Systematic Review
Regional disparities within the EU remain a persistent challenge, demanding comprehensive research. Enhancing cohesion and convergence while promoting sustainability between and within its regions is crucial to addressing these disparities.
Alexandre Canário Borrega +2 more
semanticscholar +2 more sources
Global Collaborative Social Network (Share4Rare) to Promote Citizen Science in Rare Disease Research: Platform Development Study [PDF]
BackgroundRare disease communities are spread around the globe and segmented by their condition. Little research has been performed on the majority of rare diseases.
Radu, Roxana +12 more
doaj +2 more sources
Metastatic pulmonary calcification: First report of pulmonary calcium suppression using dual-energy CT [PDF]
Metastatic pulmonary calcification is an underdiagnosed metabolic lung disease characterized by diffuse calcium deposition in the lungs, often associated with secondary hyperparathyroidism due to chronic renal failure.
Ana Fehrmann +7 more
doaj +2 more sources
[Management of side effects of CAR T cells]. [PDF]
CAR(„chimeric antigen receptor“)-T-Zell-Therapien haben die Behandlungsergebnisse bei Patient:innen mit hämatologischen Neoplasien deutlich verbessert und mit sechs zugelassenen CAR-T-Zell-Produkten ist eine gewisse Routine in der Anwendung entstanden ...
Bach F +3 more
europepmc +2 more sources

