Results 41 to 50 of about 53,316 (162)

Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. [PDF]

, 2020
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients
Ahmed, Mohamed Sohail, Ambati, Aditya, Inayathullah, Mohammed, Mallajosyula, Venkata Vamsee Aditya, Pothineni, Venkata Raveendra, Potula, Hari-Hara SK, Rajadas, Jayakumar, Sridharan, Brindha   +7 more
core  

Lyme Borreliosis During Pregnancy [PDF]

, 2012
One of the authors (AL) presented a poster on 34 pregnancies of maternal Lyme borreliosis (Lb) in 1995. It was striking that untreated Lb associated with higher probability of adverse outcome but the number of patients were small and the statistical ...
Andrá, Norbert Solymosi
core   +2 more sources

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Molecular Microbiology, EarlyView.
A novel approach using the Pseudomonas syringae ice nucleation protein (INP) system to present Borrelia burgdorferi lipoproteins on the surface of Escherichia coli reveals conservation of complement inhibitory functions among uncharacterized OspE/F‐like leader peptide (Elp) proteins.
Nathan Hill, Lara M. Matulina, Cameron MacIntyre, M. Amine Hassani, Sheila Thomas, Matteo Luban, Isabelle Ward, Amina Abdalla, John M. Leong, Brandon L. Garcia, Jacob E. Lemieux   +10 more
wiley   +1 more source

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya, Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, Kwang-Min, Maguire, Peter, Parekh, Mansi B, Pothineni, Venkata Raveendra, Potula, Hari-Hara Sk, Rajadas, Jayakumar, Tayebi, Lobat   +9 more
core  

The Flagellin‐Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

Molecular Microbiology, EarlyView.
FliS, a flagellin protein chaperon of the Lyme disease pathogen Borrelia burgdorferi, controls the cytoplasmic pool of flagellins (FlaB) at the level of translation initiation, secretion, and proteolysis. Deletion of fliS blocks FlaB secretion and translation initiation through a pattern‐switching mechanism of FliS‐FlaB‐FliW/CsrA. Therefore, the mutant
Ching Wooen Sze, Kai Zhang, Michael J. Lynch, Wangbiao Guo, Jun Liu, Brian R. Crane, Chunhao Li   +6 more
wiley   +1 more source

Diverse tick-borne microorganisms identified in free-living ungulates in Slovakia [PDF]

, 2018
Background: Free-living ungulates are hosts of ixodid ticks and reservoirs of tick-borne microorganisms in central Europe and many regions around the world.
A Alberti, A Mysterud, A Nahayo, A Obiegala, A Ohlson, A Ortuňo, A Pereira, A Pereira, A Rizzoli, A Zintl, AO Michel, AS Faria, B Flaisz, B Skotarczak, B Víchová, BL Herwaldt, C Billinis, C Huhn, C Kiffner, C Kiffner, C Martin, C Silaghi, C Silaghi, C Silaghi, CA Becker, D Duh, D González-Barrio, D Hulinska, D Hulínská, D Žele, E Dorko, E Overzier, E Overzier, E Špitalská, E Špitalská, Elena Kocianová, Eva Špitalská, F Strle, F Veronesi, FCA Pacilly, H Polin, H Sprong, H Sprong, H-P Fuehrer, Hein Sprong, HK Hinaidy, HS Ginsberg, I Baráková, I Baráková, J García-Sanmartín, J Gray, J Hapunik, J Michalik, J Michalik, J Nosek, J Stańczak, J Řeháček, J Řeháček, JM Medlock, JM Rijks, JS Liz, JW Courtney, K Häselbarth, K Kurtenbach, K Reiterová, K Siuda, K Stefanidesova, K Strasek Smrdel, K Tamura, K Štefanidesová, KT Friedhoff, L Berthová, L Gilbert, L Lempereur, L Lempereur, L Malandrin, L Minichová, L Qviller, L Tomassone, Lenka Mahríková, Lenka Minichová, Leonhard Schnittger, M Adamska, M Battilani, M Derdáková, M Di Domenico, M Jouglin, M Kauffmann, M Kazimírová, M Maurin, M Petrovec, M Petrovec, M Pfäffle, M Salman, M Sawczuk, M Sawczuk, Manoj Fonville, MJ Yabsley, MO Andersson, MP Tampieri, Mária Kazimírová, N Saitou, NS Alexander, O Rosef, P Heyman, P Zeman, R Cézanne, R Galuppi, R Welc-Falęciak, Radoslav Caban, RC Galindo, RF Massung, RL Regnery, S Casati, S Hornok, S Hornok, S Hornok, S Jahfari, S Jahfari, S Kumar, S Schorn, S Stuen, S Stuen, S Stuen, S Zanet, SE Randolph, SE Randolph, T Dugat, T Dugat, T Kiss, T Vor, TR Hofmeester, U Mackenstedt, V Tagliapietra, V Černý, VV Ebani, VV Ebani, VV Ebani, VV Ebani, W Scharf, Z Hamšíková, Z Hamšíková, Z Hamšíková Svitálková, Z Woldehiwet, Zuzana Hamšíková, Ø Hammer, Ø Øines   +146 more
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Spatial and temporal analyses of Dermacentor variabilis (Say) (Acari: Ixodidae) in central and eastern Canada

Medical and Veterinary Entomology, EarlyView.
One thousand one hundred ninety‐eight adult Dermacentor variabilis (Say), a species of veterinary and human medical importance, were collected from companion animals in central and eastern Canada. Peaks in adult D. variabilis submissions occurred in May and June across the provinces. Most submissions of adult D.
Grace K. Nichol, J. Scott Weese, Shaun J. Dergousoff, Amy L. Greer, Katie M. Clow   +4 more
wiley   +1 more source

Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. [PDF]

, 1992
We used polyclonal antisera and monoclonal antibodies (mAbs) to inhibit the growth of clonal populations of two strains of Borrelia burgdorferi, the Lyme disease agent, and thereby select for antibody-resistant mutants.
Barbour, AG, Hogan, DM, Rosa, PA, Sădziene, A, Thompson, PA   +4 more
core  

Increasing Prevalence of Syphilis: Oral Manifestations, Diagnosis and Management

Oral Surgery, EarlyView.
ABSTRACT Introduction Cases of syphilis are increasing, with 9513 cases diagnosed in England in 2023, the highest annual number since 1948. Oral healthcare professionals should therefore be aware of how oral syphilis presents, the differential diagnosis and the appropriate care pathway and management.
C. C. Currie, A. Chambers, S. Endersby, R. Green, D. A. Price, N. Robinson, E. Spoor, A. Wilson, M. Robinson   +8 more
wiley   +1 more source

The chemokine CXCL13 in acute neuroborreliosis [PDF]

, 2009
Objective Recent studies have suggested an important role of the B cell chemoattractant CXCL13 in acute neuroborreliosis (NB). Our aim was to confirm the diagnostic role of CXCL13 and to evaluate its relevance as a therapy response and disease activity ...
Brettschneider, Johannes, Ludolph, Albert C., Pfister, Hans-Walter, Rupprecht, Tobias A., Senel, Makbule, Tumani, Hayrettin   +5 more
core   +3 more sources