Results 11 to 20 of about 2,769 (164)

Tick-to-host transmission differs between Borrelia afzelii strains [PDF]

Microbiology Spectrum, 2023
ABSTRACT Many vector-borne pathogens establish multiple-strain infections in the vertebrate host and the arthropod vector. Multiple-strain infections in the host influence strain acquisition by naive vectors. Whether multiple-strain infections in the vector influence strain-specific transmission to naive hosts remains unknown ...
Dolores Genné, Whitney Jiricka, Anouk Sarr, Maarten J. Voordouw   +3 more
openaire   +4 more sources

Borrelia afzeliialters reproductive success in a rodent host [PDF]

Proceedings of the Royal Society B: Biological Sciences, 2018
The impact of a pathogen on the fitness and behaviour of its natural host depends upon the host–parasite relationship in a given set of environmental conditions. Here, we experimentally investigated the effects ofBorrelia afzelii,one of the aetiological agents of Lyme disease in humans, on the fitness of its natural rodent host, the bank vole (Myodes ...
Giermek, Anna, Gomez-Chamorro, Andrea, Hytönen, Jukka, Kallio, Eva, Mappes, Tapio, Salo, Jemiina, Voordouw, Maarten Jeroen, Koskela, Esa, Cayol, Claire   +9 more
openaire   +9 more sources

Aseptic Meningitis Linked to Borrelia afzelii Seroconversion in Northeastern Greece: An Emerging Infectious Disease Contested in the Region [PDF]

Tropical Medicine and Infectious Disease
Borreliosis (Lyme disease) is a zoonosis, mediated to humans and small mammals through specific vectors (ticks), with increasing global incidence. It is associated with a variety of clinical manifestations and can, if not promptly recognized and left ...
Dimitrios Kouroupis, Maria Terzaki, Nikoletta Moscha, Anastasia Sarvani, Elisavet Simoulidou, Sofia Chatzimichailidou, Evangelia Giza, Georgios Sapouridis, Emmanouil Angelakis, Konstantinos Petidis, Athina Pyrpasopoulou   +10 more
doaj   +2 more sources

Optimising Transformation Efficiency in Borrelia: Unravelling the Role of the Restriction-Modification System of Borrelia afzelii and Borrelia garinii [PDF]

International Journal of Molecular Sciences
Borrelia spp. are transmitted to humans by the bite of an infected tick. In Europe, Borrelia afzelii and Borrelia garinii are the main causative agents of Lyme borreliosis, one of the most prevalent tick-borne diseases in the northern hemisphere. In bacteria such as Borrelia spp., a restriction-modification system (RMS) protects against the harmful ...
Margarida Ruivo, Noémi Zsuzsa Kovács, Anna-Margarita Schötta, Theresa Stelzer, Laura Hermann, Verena Mündler, Andreas Bergthaler, Michael Reiter, Michiel Wijnveld   +8 more
openaire   +3 more sources

Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus [PDF]

Microbiome, 2023
Background Ticks can transmit a broad variety of pathogens of medical importance, including Borrelia afzelii, the causative agent of Lyme borreliosis in Europe.
Alejandra Wu-Chuang, Lourdes Mateos-Hernandez, Apolline Maitre, Ryan O. M. Rego, Radek Šíma, Stefania Porcelli, Sabine Rakotobe, Angélique Foucault-Simonin, Sara Moutailler, Vaidas Palinauskas, Justė Aželytė, Ladislav Sǐmo, Dasiel Obregon, Alejandro Cabezas-Cruz   +13 more
doaj   +2 more sources

Borrelia afzelii Hepatitis in Patient Treated with Venetoclax and Obinutuzumab, Switzerland [PDF]

Emerging Infectious Diseases
We report Borrelia afzelii hepatitis in an immunosuppressed patient in Switzerland receiving anti-CD20 therapy and venetoclax. Diagnosis was made by metagenomic sequencing and PCR. This case underscores the need to consider Lyme borreliosis in unexplained hepatitis cases and highlights the value of molecular diagnostics in immunosuppressed patients ...
Capoferri, Gioele, Battegay, Raphael, Hamelin, Baptiste, Keller, Peter M., Mertz, Kirsten D., Weisser, Maja   +5 more
openaire   +3 more sources

Genomic and phenotypic characterization of Borrelia afzelii BO23 and Borrelia garinii CIP 103362 [PDF]

PLOS ONE, 2018
In recent years, the number of Lyme disease or borreliosis cases in Eurasia has been dramatically increasing. This tick-borne disease is caused by Borrelia burgdorferi sensu lato, which includes B. burgdorferi sensu stricto, the main species found in North America, and B. afzelii and B.
Sébastien Bontemps-Gallo, Kevin A. Lawrence, Crystal L. Richards, Frank C. Gherardini   +3 more
openaire   +5 more sources

Spatial modeling of Borrelia genospecies in human-biting ticks from the French citizen science programme CiTIQUE [PDF]

Scientific Reports
In Europe, Lyme borreliosis is the most common vector-borne human disease, mainly caused by Borrelia afzelii and Borrelia garinii, two species of the Borrelia burgdorferi sensu lato (Bbsl) complex transmitted by Ixodes ricinus. Assessing the spatial risk
Thierno Madiou Bah, Jonas Durand, Arnaud Cougoul, William Wint, Francesca Dagostin, Isabelle Lebert, Magalie René-Martellet, Thomas Opitz, Xavier Bailly, Pascale Frey-Klett, Karine Chalvet-Monfray   +10 more
doaj   +2 more sources

Genetic Diversity of Siberian Isolates of Borrelia burgdorferi Sensu Lato by the ospA Gene [PDF]

Microorganisms
The genetic diversity of the ospA gene of the Borrelia burgdorferi sensu lato species complex encoding outer surface protein A has been widely investigated.
Yana Igolkina, Vera Rar, Valeriy Yakimenko, Alevtina Bardasheva, Valeria Fedorets, Alfrid Karimov, Gavril Rubtsov, Tamara Epikhina, Nina Tikunova   +8 more
doaj   +2 more sources

The First Study of Borrelia burgdorferi Sensu Lato Persistence in Small Mammals Captured in the Ixodes persulcatus Distribution Area in Western Siberia [PDF]

Pathogens
Borrelia burgdorferi sensu lato (s.l.) persistence in reservoir hosts is essential for the maintenance of the spirochaetes in the enzootic cycle. In this study, we investigated the persistence of Siberian B. burgdorferi s.l. strains in naturally infected
Vera Rar, Valeriy Yakimenko, Yana Igolkina, Yuliya Sabitova, Valeria Fedorets, Alfrid Karimov, Gavril Rubtsov, Tamara Epikhina, Nina Tikunova   +8 more
doaj   +2 more sources