Complementation of a Borrelia afzelii OspC mutant highlights the crucial role of OspC for dissemination of Borrelia afzelii in Ixodes ricinus [PDF]
Alteration of the outer surface protein (Osp) composition--especially that of OspA and OspC--seems to be important for the adaptation of Borrelia burgdorferi sensu lato to its endothermic hosts (mammals) and poikilothermic vectors (ticks). OspA possibly mediates adherence to tick midgut cells thus enabling the borreliae to survive in the vector, while ...
Volker, Fingerle +4 more
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Decorin Binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi Sensu Stricto [PDF]
Decorin adherence is crucial in the pathogenesis of Lyme borreliosis. Decorin-binding proteins (Dbp) A and B are the adhesins that mediate this interaction. DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi sensu stricto (ss) differ in their amino acid sequence, but little attention has been paid to the potential difference in ...
Salo Jemiina +5 more
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Lyme disease is a tick-borne infectious disease caused by the Borrelia burgdorferi sensu lato complex. However, the distribution of Borrelia genospecies and the tissue detection rate of Borrelia in wild rodents have rarely been investigated.
Choon Mee Kim +4 more
doaj +1 more source
Early cytokine release in response to live Borrelia burgdorferi Sensu Lato Spirochetes is largely complement independent. [PDF]
AIM: Here we investigated the role of complement activation in phagocytosis and the release of cytokines and chemokines in response to two clinical isolates: Borrelia afzelii K78, which is resistant to complement-mediated lysis, and Borrelia garinii LU59,
Kerstin Sandholm +7 more
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Complement has been considered as an important factor impacting the host–pathogen association of spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and may play a role in the spirochete’s ecology.
Valerie Sürth +4 more
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Genetic Markers for Detecting the DNA of Pathogenic Borrelia
The aim of the study was to analyze the genetic markers of Lyme disease pathogens, which can be used to specifically indicate maximum number of their strains and isolates. Materials and methods.
N. I. Khammadov, A. I. Khamidullina
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Genospecies Diversity of Borrelia in Ixodes Ticks of the West Siberia
Objective: to determine genospecies composition of Borrelia in the ixodid ticks of various species in natural foci of Ixodes tick-borne borreliosis (ITB) in the South of Western Siberia. Materials and methods.
S. A. Rudakova +5 more
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Characteristics of spirochetemic patients with a solitary erythema migrans skin lesion in Europe.
Neither pre-treatment characteristics, nor the outcome after antibiotic therapy, have been reported for spirochetemic European patients with Lyme borreliosis.
Vera Maraspin +7 more
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Association of Borrelia afzelii with rodents in Europe
Borrelia burgdorferi sensu lato (s.l.) is maintained in nature by complex zoonotic transmission cycles, involving a large variety of vertebrates as hosts and hard ticks of the genus Ixodes as vectors. Recent studies suggest that the genospecies of B. burgdorferi s.l.
K, Hanincová +7 more
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In vitro susceptibility of Borrelia afzelii, the causative agent of Lyme borreliosis, to the supernatants of Lactiplantibacillus plantarum and Saccharomyces boulardii [PDF]
Introduction: Lyme borreliosis (LB) is a multisystem disorder caused by bacteria of the Borrelia burgdorferi sensu lato complex, transmitted to humans through the bite of Ixodes spp. ticks.
Jevremović Kristina +6 more
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