Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]
, 2013 Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Christine Skerka +24 more
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Fine FocusSince its recent discovery in the late 1970s, Lyme Disease (LD) has been a growing public health concern, especially in the United States where it accounts for the majority of vector-borne infections each year. The causative agent, Borrelia burgdorferi, is transmitted to humans through the bite of an infected Ixodes tick. This pathogen uses many unique
Andrew Gaetano, Elizabeth Danka
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The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]
, 2015 The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Brown, G. +9 more
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Borrelia burgdorferi sensu lato, the agent of Lyme borreliosis: life in the wilds
Parasite, 2008 In Europe, Borrelia burgdorferi sensu lato (sl) the agent of Lyme borreliosis circulates in endemic areas between Ixodes ricinus ticks and a large number of vertebrate hosts upon which ticks feed.
Gern L.
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Diagnostic value of PCR analysis of synovial fluid for the diagnosis of Lyme borreliosis in dogs [PDF]
Науковий вісник ветеринарної медицини, 2023 Lyme borreliosis, also known as Lyme disease, is a chronic multiorgan disease of humans and animals transmitted by ticks of the Ixodidae family and caused by a group of spirochetes Borrelia burgdorferi sensu lato.
Panteleienko O., Tsarenko T.
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Identification and Structural Characterisation of Novel Outer Membrane Proteins in the genus Borrelia [PDF]
Although considered Gram-negative the outer membrane (OM) of Borrelia is unique, consisting of a variety of glycolipids, a significant number of surface exposed lipoproteins and a smaller number of integral membrane-spanning β-barrels.
Dyer, Adam
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Prevalence of G class antibodies to antigens of lyme disease causes in dogs in Vojvodina, Serbia [PDF]
Veterinarski Glasnik, 2013 Lyme disease is a multisystemic disease, zoonotic in nature, caused by the Borrelia burgdorferi sensu lato complex. In the continent of Europe, these spirochetes are predominantly transmitted by ticks of the genus Ixodes. Small mammals and birds
Potkonjak Aleksandar +6 more
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Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4 [PDF]
, 2010 Background: B. burgdorferi sensu lato (sl) is the etiological agent of Lyme borreliosis in humans. Spirochetes have adapted themselves to the human immune system in many distinct ways.
Peter F. Zipfel +22 more
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Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis
Scientific Reports, 2021 BB0405 is a surface exposed Borrelia burgdorferi protein and its vaccination protected mice against B. burgdorferi infection. As BB0405 is highly conserved across different B.
M. J. Klouwens +8 more
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Microorganisms, 2021 Ticks are widely distributed across the globe, serving as hosts for numerous pathogens that make them major contributors to zoonotic parasitosis. Borrelia burgdorferi is a bacterial species that causes an emerging zoonotic tick-borne disease known as ...
Sabir Hussain +7 more
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