Results 1 to 10 of about 417,575 (218)

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis. [PDF]

PLoS Pathogens
The role of antibodies in the host response against Mycobacterium tuberculosis (M. tb) bacteria is still poorly understood. We previously isolated two monoclonal antibodies (mAbs), p4-36 and p4-163, from an M.
Akanksha, Rania Bouzeyen, Avia Watson, Gil Wiseglass, Nyaradzai Sithole, Lilach Abramovitz, Noam Ben-Shalom, Rotem Rubinstein, Babak Javid, Natalia T Freund   +9 more
doaj   +2 more sources

Novel antibody assessment method for microbial compositional alteration in the oral cavity

Biochemistry and Biophysics Reports, 2022
Recently, it has been demonstrated that dysbiosis, an alteration in commensal microflora composition, is intimately involved in the onset of a variety of diseases.
Sumire Hoashi-Takiguchi, Hirobumi Morisaki, Momoe Itsumi, Mariko Kikuchi, Haruka Fukamachi, Mie Kurosawa, Michi Yamada, Noriyuki Suzuki, Hirotaka Kuwata   +8 more
doaj   +1 more source

Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. [PDF]

PLoS ONE, 2013
Spondyloarthritis (SpA) comprises a heterogeneous group of inflammatory diseases, with strong association to human leukocyte antigen (HLA)-B27. A triggering bacterial infection has been considered as the cause of SpA, and bacterial heat shock protein ...
Astrid Hjelholt, Thomas Carlsen, Bent Deleuran, Anne Grethe Jurik, Berit Schiøttz-Christensen, Gunna Christiansen, Svend Birkelund   +6 more
doaj   +1 more source

Removal of natural anti-αGal antibodies elicits protective immunity against Gram-negative bacterial infections

Frontiers in Immunology, 2023
Antibody-dependent enhancement (ADE) of bacterial infections occurs when blocking or inhibitory antibodies facilitate the infectivity of pathogens. In humans, antibodies involved in ADE of bacterial infections may include those naturally produced against
Sara Olivera-Ardid, Daniel Bello-Gil, Magdiel Perez-Cruz, Cristina Costa, Mariana Camoez, Mariana Camoez, M. Angeles Dominguez, M. Angeles Dominguez, Yara Ferrero-Alves, Jose Miguel Vaquero, Nailya Khasbiullina, Nadezhda V. Shilova, Nicolai V. Bovin, Rafael Mañez, Rafael Mañez   +14 more
doaj   +1 more source

Functional Activity of Antibodies Directed towards Flagellin Proteins of Non-Typhoidal Salmonella. [PDF]

PLoS ONE, 2016
Non-typhoidal Salmonella (NTS) serovars Typhimurium and Enteritidis are major causes of invasive bacterial infections in children under 5 years old in sub-Saharan Africa, with case fatality rates of ~20%.
Girish Ramachandran, Sharon M Tennant, Mary A Boyd, Jin Y Wang, Mohan E Tulapurkar, Marcela F Pasetti, Myron M Levine, Raphael Simon   +7 more
doaj   +1 more source

Compensatory intestinal immunoglobulin response after vancomycin treatment in humans

Gut Microbes, 2021
Intestinal immunoglobulins (Ig) are abundantly secreted antibodies that bind bacteria and bacterial components in the gut. This binding is considered to accelerate bacterial transit time and prevent the interaction of potentially immunogenic compounds ...
Torsten P. M. Scheithauer, Guido J. Bakker, Maaike Winkelmeijer, Mark Davids, Max Nieuwdorp, Daniël H. van Raalte, Hilde Herrema   +6 more
doaj   +1 more source

Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

npj Vaccines, 2021
Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced
Lionel K. K. Tan, Mark Reglinski, Daryl Teo, Nada Reza, Lucy E. M. Lamb, Vaitehi Nageshwaran, Claire E. Turner, Mats Wikstrom, Inga-Maria Frick, Lars Bjorck, Shiranee Sriskandan   +10 more
doaj   +1 more source

A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis

Frontiers in Immunology, 2021
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu, Wenyan Fu, Yu Liu, Yu Liu, Fangjie Liu, Fangjie Liu, Chenghua Liu, Chenghua Liu, Jingjing Li, Jiali Niu, Peng Han, Dan Xu, Jiaojiao Hou, Yuanfang Ma, Jiannan Feng, Jiannan Feng, Zhanguo Li, Rong Mu, Guang Yang, Guang Yang   +19 more
doaj   +1 more source

Altered functionality of anti-bacterial antibodies in patients with chronic hepatitis C virus infection. [PDF]

PLoS ONE, 2013
Using comparative glycoproteomics, we have previously identified a glycoprotein that is altered in both amount and glycosylation as a function of liver cirrhosis.
Anne Lamontagne, Ronald E Long, Mary Ann Comunale, Julie Hafner, Lucy Rodemich-Betesh, Mengjun Wang, Jorge Marrero, Adrian M Di Bisceglie, Timothy Block, Anand Mehta   +9 more
doaj   +1 more source

Therapeutic effect of polyclonal lipoprotein SA2275 antibodies on Staphylococcus aureus-induced brain abscess in mice

Di-san junyi daxue xuebao, 2020
Objective To investigate the ability of specific polyclonal antibodies against Staphylococcus aureus (S. aureus) lipoprotein SA2275 to penetrate the blood-brain barrier for inhibiting the formation of S. aureus-induced brain abscess in mice.
ZHENG Ying, ZHENG Ying, YANG Yi, PENG Huagang   +3 more
doaj   +1 more source