Results 1 to 10 of about 400,807 (164)

Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages [PDF]

mBio
Antibodies against Salmonella Typhimurium (STm) can provide protection against infection. Understanding how antibodies, complement, and leukocytes interact is essential and can help advance vaccine development.
Marisol Perez-Toledo, Kubra Aksu-Istil, Edith Marcial-Juarez, Ruby R. Persaud, Areej Alshayea, Sian E. Jossi, Agostina Carestia, Fien von Meijenfeld, Marina Botto, Leo C. James, Bas Surewaard, Zaheer Afzal, Adrian M. Shields, William G. Horsnell, Constantino Lopez-Macias, Ian R. Henderson, Craig N. Jenne, Adam F. Cunningham   +17 more
doaj   +2 more sources

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis. [PDF]

PLoS Pathogens
The role of antibodies in the host response against Mycobacterium tuberculosis (M. tb) bacteria is still poorly understood. We previously isolated two monoclonal antibodies (mAbs), p4-36 and p4-163, from an M.
Akanksha, Rania Bouzeyen, Avia Watson, Gil Wiseglass, Nyaradzai Sithole, Lilach Abramovitz, Noam Ben-Shalom, Rotem Rubinstein, Babak Javid, Natalia T Freund   +9 more
doaj   +2 more sources

Novel antibody assessment method for microbial compositional alteration in the oral cavity

Biochemistry and Biophysics Reports, 2022
Recently, it has been demonstrated that dysbiosis, an alteration in commensal microflora composition, is intimately involved in the onset of a variety of diseases.
Sumire Hoashi-Takiguchi, Hirobumi Morisaki, Momoe Itsumi, Mariko Kikuchi, Haruka Fukamachi, Mie Kurosawa, Michi Yamada, Noriyuki Suzuki, Hirotaka Kuwata   +8 more
doaj   +1 more source

Monoclonal antibodies and bacterial virulence [PDF]

Virulence, 2017
This issue of Virulence features an article entitled “Antibodies to Staphylococcus aureus capsular polysaccharides 5 and 8 perform similarly in vitro but are functionally distinct in vivo”1 which d...
Mirella, Luciani, Luigi, Iannetti
openaire   +2 more sources

Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. [PDF]

PLoS ONE, 2013
Spondyloarthritis (SpA) comprises a heterogeneous group of inflammatory diseases, with strong association to human leukocyte antigen (HLA)-B27. A triggering bacterial infection has been considered as the cause of SpA, and bacterial heat shock protein ...
Astrid Hjelholt, Thomas Carlsen, Bent Deleuran, Anne Grethe Jurik, Berit Schiøttz-Christensen, Gunna Christiansen, Svend Birkelund   +6 more
doaj   +1 more source

Removal of natural anti-αGal antibodies elicits protective immunity against Gram-negative bacterial infections

Frontiers in Immunology, 2023
Antibody-dependent enhancement (ADE) of bacterial infections occurs when blocking or inhibitory antibodies facilitate the infectivity of pathogens. In humans, antibodies involved in ADE of bacterial infections may include those naturally produced against
Sara Olivera-Ardid, Daniel Bello-Gil, Magdiel Perez-Cruz, Cristina Costa, Mariana Camoez, Mariana Camoez, M. Angeles Dominguez, M. Angeles Dominguez, Yara Ferrero-Alves, Jose Miguel Vaquero, Nailya Khasbiullina, Nadezhda V. Shilova, Nicolai V. Bovin, Rafael Mañez, Rafael Mañez   +14 more
doaj   +1 more source

Specificity of secretory antibodies to bacterial immunogens [PDF]

Infection and Immunity, 1976
The present investigation examined the specificity of the salivary immune response of axenic and conventional mice to topically administered Salmonella typhi, S. gallinarum, and S. typhimurium. Specific antibacterial antibodies were determined by passive hemagglutination and bacterial agglutination. Reciprocal antibody titers up to 320 were detected in
J L, Ebersole, J A, Molinari
openaire   +2 more sources

Functional Activity of Antibodies Directed towards Flagellin Proteins of Non-Typhoidal Salmonella. [PDF]

PLoS ONE, 2016
Non-typhoidal Salmonella (NTS) serovars Typhimurium and Enteritidis are major causes of invasive bacterial infections in children under 5 years old in sub-Saharan Africa, with case fatality rates of ~20%.
Girish Ramachandran, Sharon M Tennant, Mary A Boyd, Jin Y Wang, Mohan E Tulapurkar, Marcela F Pasetti, Myron M Levine, Raphael Simon   +7 more
doaj   +1 more source

Compensatory intestinal immunoglobulin response after vancomycin treatment in humans

Gut Microbes, 2021
Intestinal immunoglobulins (Ig) are abundantly secreted antibodies that bind bacteria and bacterial components in the gut. This binding is considered to accelerate bacterial transit time and prevent the interaction of potentially immunogenic compounds ...
Torsten P. M. Scheithauer, Guido J. Bakker, Maaike Winkelmeijer, Mark Davids, Max Nieuwdorp, Daniël H. van Raalte, Hilde Herrema   +6 more
doaj   +1 more source

Inhibition of Bacterial Superantigens by Peptides and Antibodies [PDF]

Infection and Immunity, 2001
ABSTRACT The pyrogenic exotoxins of group A streptococci and staphylococcal enterotoxins are a family of structurally related superantigens with similar biological activity. Two distinct areas have been identified which have a highly conserved amino acid homology in all of the toxin families. A number of peptides were constructed from
K, Visvanathan, A, Charles, J, Bannan, P, Pugach, K, Kashfi, J B, Zabriskie   +5 more
openaire   +3 more sources