Results 11 to 20 of about 413,379 (310)

Polyclonal antibodies inhibit growth of key cellulolytic rumen bacterial species [PDF]

Frontiers in Microbiology, 2023
Antibodies targeting specific bacterial species could allow for modification of the rumen microbial population to enhance rumen fermentation. However, there is limited knowledge of targeted antibody effects on rumen bacteria. Therefore, our objective was
Sara M. Tondini, Roderick I. Mackie, Roderick I. Mackie, Joshua C. McCann   +3 more
doaj   +2 more sources

Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

npj Vaccines, 2021
Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced
Lionel K. K. Tan, Mark Reglinski, Daryl Teo, Nada Reza, Lucy E. M. Lamb, Vaitehi Nageshwaran, Claire E. Turner, Mats Wikstrom, Inga-Maria Frick, Lars Bjorck, Shiranee Sriskandan   +10 more
doaj   +1 more source

A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis

Frontiers in Immunology, 2021
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu, Wenyan Fu, Yu Liu, Yu Liu, Fangjie Liu, Fangjie Liu, Chenghua Liu, Chenghua Liu, Jingjing Li, Jiali Niu, Peng Han, Dan Xu, Jiaojiao Hou, Yuanfang Ma, Jiannan Feng, Jiannan Feng, Zhanguo Li, Rong Mu, Guang Yang, Guang Yang   +19 more
doaj   +1 more source

Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB₂ in malaria exposed individuals [PDF]

, 2009
Background MB2 protein is a sporozoite surface antigen on the human malaria parasite Plasmodium falciparum. MB2 was identified by screening a P. falciparum sporozoite cDNA expression library using immune sera from a protected donor immunized via the ...
James Anthony A, de la Vega, Patricia, John, Chandy C, Thanh V Nguyen, Nguyen, Thanh V, de la Vega, P, John B Sacci, Patricia de la Vega, James, Anthony A, Kang Angray S, John Chandy C, James, AA, Nguyen, T.V., Sacci, John B, Kang, A.S., Sacci John B, de la Vega, P., Nguyen Thanh V, Anthony A James, de la Vega Patricia, John, C.C., Kang, Angray S, Angray S Kang, Sacci, J.B., Patricia Vega, Chandy C John, John, CC, Nguyen, TV, Kang, AS, Jr, SJB, James, A.A.   +30 more
core   +1 more source

Altered functionality of anti-bacterial antibodies in patients with chronic hepatitis C virus infection. [PDF]

PLoS ONE, 2013
Using comparative glycoproteomics, we have previously identified a glycoprotein that is altered in both amount and glycosylation as a function of liver cirrhosis.
Anne Lamontagne, Ronald E Long, Mary Ann Comunale, Julie Hafner, Lucy Rodemich-Betesh, Mengjun Wang, Jorge Marrero, Adrian M Di Bisceglie, Timothy Block, Anand Mehta   +9 more
doaj   +1 more source

Therapeutic effect of polyclonal lipoprotein SA2275 antibodies on Staphylococcus aureus-induced brain abscess in mice

Di-san junyi daxue xuebao, 2020
Objective To investigate the ability of specific polyclonal antibodies against Staphylococcus aureus (S. aureus) lipoprotein SA2275 to penetrate the blood-brain barrier for inhibiting the formation of S. aureus-induced brain abscess in mice.
ZHENG Ying, ZHENG Ying, YANG Yi, PENG Huagang   +3 more
doaj   +1 more source

Investigation of Cas9 antibodies in the human eye

Nature Communications, 2022
Pre-existing antibodies against Cas9 proteins represent a potential issue for gene therapies, including those targeting the eye. Here the authors assess the presence of intraocular antibodies, and show that Cas9 antibodies were prevalent in human serum ...
Marcus A. Toral, Carsten T. Charlesworth, Benjamin Ng, Teja Chemudupati, Shota Homma, Hiromitsu Nakauchi, Alexander G. Bassuk, Matthew H. Porteus, Vinit B. Mahajan   +8 more
doaj   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Virók Dezső, Gönczöl Éva, Prohászka Zoltán, Burián, Katalin, Endrész Valéria, Duba Jenő, Füst György, Kis, Zoltán, Virók, Dezső, Endrész, Valéria, Duba, Jenő, Boda, Krisztina, Berencsi Klára, Berencsi, Klára, Kis Zoltán, Romics, László, Romics László, Gönczöl, Éva, Prohászka, Zoltán, Horváth, Laura, Boda Krisztina, Burián Katalin, Horváth Laura, Füst, György   +23 more
core   +1 more source

Presence of anti-microbial antibodies in liver cirrhosis--a tell-tale sign of compromised immunity? [PDF]

PLoS ONE, 2010
BACKGROUND: Bacterial translocation plays important role in the complications of liver cirrhosis. Antibody formation against various microbial antigens is common in Crohn's disease and considered to be caused by sustained exposure to gut microflora ...
Maria Papp, Gary L Norman, Zsuzsanna Vitalis, Istvan Tornai, Istvan Altorjay, Ildiko Foldi, Miklos Udvardy, Zakera Shums, Tamas Dinya, Peter Orosz, Bela Lombay, Gabriella Par, Alajos Par, Gabor Veres, Timea Csak, Janos Osztovits, Ferenc Szalay, Peter Laszlo Lakatos   +17 more
doaj   +1 more source

A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry

Clinical and Developmental Immunology, 2008
We previously demonstrated that purified polyclonal and monoclonal anti-dsDNA antibodies bind a 15-mer peptide ASPVTARVLWKASHV in ELISA and Dot blot. This 15-mer peptide partial sequence ARVLWKASH shares similarity with burkholderia bacterial cytochrome ...
Wei Zhang, Morris Reichlin
doaj   +1 more source