Results 71 to 80 of about 37,258 (181)

Climate change and habitat fragmentation drive the occurrence of Borrelia burgdorferi, the agent of Lyme disease, at the northeastern limit of its distribution

Evolutionary Applications, 2014
Lyme borreliosis is rapidly emerging in Canada, and climate change is likely a key driver of the northern spread of the disease in North America. We used field and modeling approaches to predict the risk of occurrence of Borrelia burgdorferi, the ...
J. Simon, Robby R. Marrotte, Natalie Desrosiers, Jessica Fiset, J. Gaitán, Andrew Gonzalez, J. Koffi, F. Lapointe, P. Leighton, L. R. Lindsay, Travis Logan, F. Milord, N. Ogden, Anita Rogic, Emilie Roy-Dufresne, D. Suter, N. Tessier, V. Millien   +17 more
semanticscholar   +1 more source

Idiosyncratic spatial scaling of biodiversity–disease relationships

Ecography, EarlyView.
High host biodiversity is hypothesized to dilute the risk of vector‐borne diseases if many host species are ‘dead ends' that cannot effectively transmit the disease and low‐diversity areas tend to be dominated by competent host species. However, many studies on biodiversity–disease relationships characterize host biodiversity at single, local spatial ...
Neil A. Gilbert, Graziella V. DiRenzo, Elise F. Zipkin   +2 more
wiley   +1 more source

Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library

Emerging Microbes and Infections, 2014
Although antibiotic treatment for Lyme disease is effective in the majority of cases, especially during the early phase of the disease, a minority of patients suffer from post-treatment Lyme disease syndrome (PTLDS).
Jie Feng, Ting Wang, W. Shi, Shuo Zhang, D. Sullivan, P. Auwaerter, Ying Zhang   +6 more
semanticscholar   +1 more source

Resurgence of Persisting Non-Cultivable Borrelia burgdorferi following Antibiotic Treatment in Mice

PLoS ONE, 2014
The agent of Lyme borreliosis, Borrelia burgdorferi, evades host immunity and establishes persistent infections in its varied mammalian hosts. This persistent biology may pose challenges to effective antibiotic treatment.
E. Hodzic, D. Imai, S. Feng, S. Barthold
semanticscholar   +1 more source

Discospondylitis as a consequence of jugular vein septic thrombophlebitis in a Standardbred gelding

Equine Veterinary Education, EarlyView.
Summary This report describes the identification of C7‐T1 discospondylitis on myelography and confirmed on postmortem computed tomography and necropsy in a 4‐year‐old Standardbred gelding as the consequence of jugular vein catheterisation and secondary septic thrombophlebitis. Staphylococcus aureus was isolated from both sites.
F. Payette, J. A. Demchur, K. W. Bills, D. G. Levine, A. L. Johnson   +4 more
wiley   +1 more source

Amplification of the flgE gene provides evidence for the existence of a Brazilian borreliosis

Revista do Instituto de Medicina Tropical de São Paulo, 2012
INTRODUCTION: The symptoms of Brazilian borreliosis resemble the clinical manifestations of Lyme disease (LD). However, there are differences between the two in terms of epidemiological and laboratory findings.
Elenice Mantovani, Roberta G. Marangoni, Giancarla Gauditano, Virgínia L.N. Bonoldi, Natalino H. Yoshinari   +4 more
doaj   +1 more source

DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. [PDF]

PLoS ONE, 2012
Lyme disease Borreliae are highly dependent on the uptake of nutrients provided by their hosts. Our study describes the identification of a 36 kDa protein that functions as putative dicarboxylate-specific porin in the outer membrane of Lyme disease ...
Marcus Thein, Mari Bonde, Ignas Bunikis, Katrin Denker, Albert Sickmann, Sven Bergström, Roland Benz   +6 more
doaj   +1 more source

Co-Infection of Blacklegged Ticks with Babesia microti and Borrelia burgdorferi Is Higher than Expected and Acquired from Small Mammal Hosts

PLoS ONE, 2014
Humans in the northeastern and midwestern United States are at increasing risk of acquiring tickborne diseases – not only Lyme disease, but also two emerging diseases, human granulocytic anaplasmosis and human babesiosis. Co-infection with two or more of
M. Hersh, R. Ostfeld, D. J. McHenry, M. Tibbetts, J. Brunner, M. Killilea, K. Logiudice, K. Schmidt, F. Keesing   +8 more
semanticscholar   +1 more source

Prognostic factors and long‐term outcome in dogs diagnosed with primary and secondary immune thrombocytopenia in Ireland

Journal of Small Animal Practice, EarlyView.
Objectives The objectives of this study were to describe the outcome and prognostic factors in dogs diagnosed with primary and secondary immune thrombocytopenia (ITP). Materials and Methods Medical records of dogs diagnosed with primary and secondary ITP in a referral hospital in Ireland were retrospectively evaluated.
E. López‐Bailén, A. Duclos, D. Mullany, K. Le Boedec, B. Cuq   +4 more
wiley   +1 more source

Lyme Disease—An Unusual Cause of a Mitral Valve Endocarditis

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018
Lyme disease is a tick-borne infection caused by Borrelia burgdorferi. Cardiac manifestations are rare, occurring in 0.5% to 10% of patients. Lyme carditis and atrioventricular block are established manifestations of Lyme disease.
Benish Fatima, MD, M. Rizwan Sohail, MD, Hartzell V. Schaff, MD   +2 more
doaj