Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4 [PDF]
Background: B. burgdorferi sensu lato (sl) is the etiological agent of Lyme borreliosis in humans. Spirochetes have adapted themselves to the human immune system in many distinct ways.
Peter F. Zipfel +22 more
core +1 more source
Disparity Between Serological Reactivity toBorrelia burgdorferiand Evidence of Past Disease in a High‐Risk Group [PDF]
A prevalence study of past Lyme borreliosis in persons with outdoor occupations was done. Consenting individuals (n = 302) were administered a questionnaire eliciting demographic and occupational data and a clinical history, and were asked to donate a serum specimen for detection of antibodies to Borrelia burgdorferi by enzyme-linked immunosorbent ...
Fernando Arteaga +7 more
openaire +2 more sources
Lyme disease (LD), also known as Lyme borreliosis and carried by Ixodes ticks, is the most common zoonotic disease in the northern hemisphere. Although the prevalence of the disease in Turkey is not known exactly, seroepidemiologic studies show that the ...
Mustafa HATİPOĞLU, Vedat TURHAN
doaj +1 more source
Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection [PDF]
The ability of vaccination with recombinant OspA from six seroprotective groups of Borrelia burgdorferi sensu lato to induce protection against infection with homologous and other Lyme spirochetes was examined in hamsters. Antisera generated against the OspA proteins of B.
S D, Lovrich +6 more
openaire +2 more sources
Comparison of Lyme Disease in the United States and Europe
Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi sensu lato bacteria species responsible for causing the infection.
Adriana R. Marques +2 more
doaj +1 more source
Multicentric Study of Seroprevalence of Borrelia Burgdorferi and Anaplasma Phagocytophila in High-Risk Groups in Regions of Central and Southern Italy [PDF]
The aim of this study was to evaluate the seroprevalence of B. burgdorferi and A. phagocytophila in populations of workers from 4 Italian regions, known to be exposed to tick bites. A total of 712 serum samples collected were divided as follows: 387 samples were obtained from workers at risk for tick bites and 325 from individuals that were not ...
SANTINO, Iolanda +8 more
openaire +4 more sources
The outer surface protein C (OspC) of the agent of Lyme disease, Borrelia burgdorferi sensu stricto, is a major lipoprotein surface-expressed during early-phase human infections. Antibodies to OspC are used in serological diagnoses. This study explored the hypothesis that serological test sensitivity decreases as genetic similarity of ospC major groups
Samir Mechai +2 more
openaire +4 more sources
Background Ixodes granulatus is widely distributed in various countries of Southeast Asia and Taiwan. Although this tick species is presumed to be the vector for the enzoonotic transmission of Borrelia spirochetes in the Taiwan area, the prevalence of ...
Chao Li-Lian +2 more
doaj +1 more source
Identification of a third genomic group of Borrelia burgdorferi through signature nucleotide analysis and 16S rRNA sequence determination [PDF]
As part of a continuing effort to assess genetic variation among isolates of Borrelia burgdorferi we have determined the 16S rRNA signature nucleotide makeup of two tick isolates from the USSR. Signature nucleotides were identified via reverse transcriptase primer extension sequencing of select regions of the 16S rRNA molecule.
R T, Marconi, C F, Garon
openaire +2 more sources
Lyme neuroborreliosis (LNB) is the most dangerous manifestation of Lyme disease caused by the spirochete Borrelia burgdorferi which can reach the central nervous system most commonly presenting with lymphocytic meningitis; however, the molecular basis ...
Zhe Ding +31 more
doaj +1 more source

