Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]
Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Glatz, Martin +5 more
core +1 more source
Lyme disease (LD), also known as Lyme borreliosis and carried by Ixodes ticks, is the most common zoonotic disease in the northern hemisphere. Although the prevalence of the disease in Turkey is not known exactly, seroepidemiologic studies show that the ...
Mustafa HATİPOĞLU, Vedat TURHAN
doaj +1 more source
Disparity Between Serological Reactivity toBorrelia burgdorferiand Evidence of Past Disease in a High‐Risk Group [PDF]
A prevalence study of past Lyme borreliosis in persons with outdoor occupations was done. Consenting individuals (n = 302) were administered a questionnaire eliciting demographic and occupational data and a clinical history, and were asked to donate a serum specimen for detection of antibodies to Borrelia burgdorferi by enzyme-linked immunosorbent ...
Fernando Arteaga +7 more
openaire +2 more sources
Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Christine Skerka +24 more
core +1 more source
Borrelia burgdorferi sensu lato (s.l.) DNA was detected by PCR in Ixodes persulcatus Schulze, 1930, Haemaphysalis concinna Koch, 1844, Haemaphysalis japonica douglasi Nuttall et Warburton, 1915 and Dermacentor silvarum Olenev, 1932 ticks collected in the
Natalia M. Pukhovskaya +4 more
doaj +1 more source
A cofactor-promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis. [PDF]
Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Paddy IA +7 more
europepmc +2 more sources
Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection [PDF]
The ability of vaccination with recombinant OspA from six seroprotective groups of Borrelia burgdorferi sensu lato to induce protection against infection with homologous and other Lyme spirochetes was examined in hamsters. Antisera generated against the OspA proteins of B.
S D, Lovrich +6 more
openaire +2 more sources
Identification and Structural Characterisation of Novel Outer Membrane Proteins in the genus Borrelia [PDF]
Although considered Gram-negative the outer membrane (OM) of Borrelia is unique, consisting of a variety of glycolipids, a significant number of surface exposed lipoproteins and a smaller number of integral membrane-spanning β-barrels.
Dyer, Adam
core +3 more sources
Comparison of Lyme Disease in the United States and Europe
Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi sensu lato bacteria species responsible for causing the infection.
Adriana R. Marques +2 more
doaj +1 more source
The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Brown, G. +9 more
core +1 more source

