Results 61 to 70 of about 7,745 (239)

Clinical Characteristics in Danish Children and Adults Diagnosed With Neuroborreliosis: A Retrospective Study From January 2016 to January 2024

European Journal of Neurology, Volume 32, Issue 7, July 2025.
ABSTRACT Introduction Lyme neuroborreliosis (NB), is caused by tick‐borne spirochetes in the Borrelia burgdorferi sensu lato (Bbsl) genospecies complex. Although the clinical manifestations of NB in adults and children are well documented, understanding neurobiological differences between these groups can improve diagnostic accuracy and treatment ...
Al‐Hasan Hussein Dos, Nina Vindegaard Sørensen, Malini Vendela Sagar, Anne‐Mette Lebech, Anders Hougaard, Christian Stenør   +5 more
wiley   +1 more source

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Molecular Microbiology, Volume 124, Issue 1, Page 77-90, July 2025.
A novel approach using the Pseudomonas syringae ice nucleation protein (INP) system to present Borrelia burgdorferi lipoproteins on the surface of Escherichia coli reveals conservation of complement inhibitory functions among uncharacterized OspE/F‐like leader peptide (Elp) proteins.
Nathan Hill, Lara M. Matulina, Cameron MacIntyre, M. Amine Hassani, Sheila Thomas, Matteo Luban, Isabelle Ward, Amina Abdalla, John M. Leong, Brandon L. Garcia, Jacob E. Lemieux   +10 more
wiley   +1 more source

Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis

Clinical and Developmental Immunology, 2012
Why some individuals develop clinical manifestations in Lyme borreliosis (LB) while others remain asymptomatic is largely unknown. Therefore, we wanted to investigate adaptive and innate immune responsiveness to Borrelia burgdorferi sensu lato in exposed
Barbro H. Skogman, Sandra Hellberg, Christina Ekerfelt, Maria C. Jenmalm, Pia Forsberg, Johnny Ludvigsson, Sven Bergström, Jan Ernerudh   +7 more
doaj   +1 more source

Infection Kinetics and Tropism of Borrelia burgdorferi sensu lato in Mouse After Natural (via Ticks) or Artificial (Needle) Infection Depends on the Bacterial Strain

Frontiers in Microbiology, 2018
Borrelia burgdorferi sl is a complex of pathogen bacteria transmitted to the host by Ixodes ticks. European Ixodes ricinus ticks transmit different B. burgdorferi species, pathogenic to human.
N. Sertour, Violaine Cotté, M. Garnier, L. Malandrin, E. Ferquel, V. Choumet   +5 more
semanticscholar   +1 more source

Permission to bite: White‐footed mice show no increased grooming response to tick infestation

Journal of Zoology, Volume 326, Issue 2, Page 140-147, June 2025.
White‐footed mice (Peromyscus leucopus) are one of the most frequently studied hosts of blacklegged ticks (Ixodes scapularis); however, interactions between white‐footed mice and ticks are not easily observed. This study aimed to quantify activity patterns in white‐footed mice and to assess their behavioral responses to parasitism by blacklegged ticks ...
J. E. Brown, P. Chuard, E. T. Machtinger
wiley   +1 more source

Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice

Ticks and Tick-borne Diseases, 2011
B. burgdorferi, B. afzelii, and B. bavariensis show resistance to mouse and human complement. B. garinii and B. valaisiana are sensitive to mouse and human complement. We evaluated whether the absence of C3 in mice influenced infectivity and pathogenicity of different Borrelia species.
Burgel, N.D. van, Balmus, N.C.M., Fikrig, E., Dam, A.P. van   +3 more
openaire   +4 more sources

A Novel High Discriminatory Protocol for the Detection of Borrelia afzelii, Borrelia burgdorferi Sensu Stricto and Borrelia garinii in Ticks

Pathogens, 2022
Bacteria of the Borrelia burgdorferi sensu lato complex are the causative agents of Lyme borreliosis (LB). Even if the conventional diagnosis of LB does not rely on the species itself, an accurate species identification within the complex will provide a ...
Giulia Chiappa, Matteo Perini, Alessandra Cafiso, Riccardo Nodari, Peter Wilhelmsson, Per-Eric Lindgren, Anna Omazic, Karin Ullman, Sara Moutailler, Petter Kjellander, Chiara Bazzocchi, Giulio Grandi   +11 more
doaj   +1 more source

The role of Mannose Binding Lectin in the immune response against Borrelia burgdorferi sensu lato

Scientific Reports, 2019
The causative agents of Lyme borreliosis, spirochetes belonging to the Borrelia burgdorferi sensu lato group, have developed several ways to protect themselves against killing by the host complement system.
J. Coumou, A. Wagemakers, S. Narasimhan, Tim J. Schuijt, J. Ersoz, Anneke Oei, O. D. de Boer, J. Roelofs, E. Fikrig, J. Hovius   +9 more
semanticscholar   +1 more source

There Goes the Neighbourhood—A Multi‐City Study Reveals Ticks and Tick‐Borne Pathogens Commonly Occupy Urban Green Spaces

Zoonoses and Public Health, Volume 72, Issue 3, Page 313-323, May 2025.
ABSTRACT Introduction Humans acquire tick‐borne pathogens (TBPs) from infected ticks contacted during outdoor activities. Outdoor activity is at its highest in urban green spaces, where the presence of tick populations has increasingly been observed. Consequently, more insight into factors influencing the presence of ticks therein is needed.
Jani J. Sormunen, Satu Kylänpää, Ella Sippola, Riikka Elo, Nosheen Kiran, Veli‐Matti Pakanen, Eva R. Kallio, Eero J. Vesterinen, Tero Klemola   +8 more
wiley   +1 more source

Population genetics, taxonomy, phylogeny and evolution of Borrelia burgdorferi sensu lato [PDF]

Infection, Genetics and Evolution, 2011
In order to understand the population structure and dynamics of bacterial microorganisms, typing systems that accurately reflect the phylogenetic and evolutionary relationship of the agents are required. Over the past 15 years multilocus sequence typing schemes have replaced single locus approaches, giving novel insights into phylogenetic and ...
Margos, Gabriele, Vollmer, Stephanie A, Ogden, Nicholas H, Fish, Durland   +3 more
openaire   +3 more sources