Results 81 to 90 of about 25,141 (238)

Navigating infection by pathogenic spirochetes: The host‐bacteria interface at the atomic level

Protein Science, Volume 34, Issue 7, July 2025.
Abstract Pathogenic spirochetes bind and interact with various host structures and molecules throughout the course of infection. By utilizing their outer surface molecules, spirochetes can effectively modulate their dissemination, interact with immune system regulators, and select specific destination niches within the host.
Libor Hejduk, Norbert Müller, Adriana Rathner, Ján Štěrba, Shang‐Cheng Hung, Chia‐Lin Chyan, Ryan O. M. Rego, Martin Strnad   +7 more
wiley   +1 more source

Emerging tick-borne infections in mainland China: an increasing public health threat [PDF]

, 2015
Since the beginning of the 1980s, 33 emerging tick-borne agents have been identified in mainland China, including eight species of spotted fever group rickettsiae, seven species in the family Anaplasmataceae, six genospecies in the complex Borrelia ...
Cao, Wu-Chun, Chen, Wan-Jun, Fang, Li-Qun, Gray, Gregory C., Jiang, Jia-Fu, Krause, Peter J., Li, Hao, Li, Xin-Lou, Liang, Song, Liu, Kun, Liu, Wei, Ma, Mai-Juan, Sun, Ruo-Xi, Sun, Ye, Yang, X. Frank, Yang, Yang, Yao, Hong-Wu, Zuo, Shu-Qing   +17 more
core   +1 more source

Clinical Characteristics in Danish Children and Adults Diagnosed With Neuroborreliosis: A Retrospective Study From January 2016 to January 2024

European Journal of Neurology, Volume 32, Issue 7, July 2025.
ABSTRACT Introduction Lyme neuroborreliosis (NB), is caused by tick‐borne spirochetes in the Borrelia burgdorferi sensu lato (Bbsl) genospecies complex. Although the clinical manifestations of NB in adults and children are well documented, understanding neurobiological differences between these groups can improve diagnostic accuracy and treatment ...
Al‐Hasan Hussein Dos, Nina Vindegaard Sørensen, Malini Vendela Sagar, Anne‐Mette Lebech, Anders Hougaard, Christian Stenør   +5 more
wiley   +1 more source

Pathogenic analysis of Borrelia garinii strain SZ isolated from northeastern China [PDF]

Parasites & Vectors, 2013
Abstract Background Various genospecies of Borrelia burgdorferi sensu lato (s.l.) have been identified from patients and animals worldwide. Genospecies-related dissemination of disease has been reported. The present study aimed to elucidate the pathogenicity of infections caused by B. garinii SZ isolated in China.
Qiong Wu, Zhijie Liu, Jidong Wang, Youquan Li, Guiquan Guan, Jifei Yang, Ze Chen, Jie Luo, Hong Yin   +8 more
openaire   +2 more sources

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Molecular Microbiology, Volume 124, Issue 1, Page 77-90, July 2025.
A novel approach using the Pseudomonas syringae ice nucleation protein (INP) system to present Borrelia burgdorferi lipoproteins on the surface of Escherichia coli reveals conservation of complement inhibitory functions among uncharacterized OspE/F‐like leader peptide (Elp) proteins.
Nathan Hill, Lara M. Matulina, Cameron MacIntyre, M. Amine Hassani, Sheila Thomas, Matteo Luban, Isabelle Ward, Amina Abdalla, John M. Leong, Brandon L. Garcia, Jacob E. Lemieux   +10 more
wiley   +1 more source

Exploring Diversity among Norwegian Borrelia Strains Originating from Ixodes ricinus Ticks

International Journal of Microbiology, 2014
Characterisation of Borrelia strains from Ixodes ricinus ticks is important in the epidemiological surveillance of vector-borne pathogens. Multilocus sequences analysis (MLSA) is a molecular genotyping tool with high discriminatory power that has been ...
Ann-Kristin Tveten
doaj   +1 more source

A mutagenic PCR identifies isolates of Borrelia garinii responsible for Lyme borreliosis [PDF]

, 2017
Borrelia garinii is one of the three major Borreliae responsible for Lyme borreliosis in Europe. We have characterized a protein of B. garinii (VS102) and a genomic fragment from the gene encoding this protein was cloned. The DNA sequence of the fragment
Bretz, Anne-Gabrielle, Hutter, Pierre, Mueller, Célia, Péter, Olivier, Sahli, Roland, Toutoungi, Lina N.   +5 more
core  

Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]

, 2008
Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Bacon RM, Bettina Wilske, Bono JL, Bruckbauer HR, Christina Ambros-Rudolph, Coleman JL, Dressler F, Engstrom SM, Feder, Fung BP, Glatz M, Goettner G, Grodzicki RL, Guo BP, Hansen K, Hauser U, Helmut Kerl, Hofmann H, Hulshof MM, Jauris-Heipke S, Kalish RA, Lahdenne P, Lebech AM, Ledue TB, Liang FT, Liang FT, Magnarelli LA, Magnarelli LA, Marangoni A, Martin Glatz, Massarotti EM, Mullegger RR, Peltomaa M, Philipp MT, Picken MM, Plorer A, Rasiah C, Robert R. Müllegger, Roessler D, Ruzic-Sabljic E, Ryffel K, Shadick NA, Sillanpaa H, Simpson WJ, Smith RP, Stanek G, Stanek G, Volker Fingerle, Volkman DJ, Wilske B, Wilske B, Wilske B, Wilske B, Wormser GP, Zhang JR   +57 more
core   +1 more source

Extravasation of Borrelia burgdorferi Across the Blood–Brain Barrier is an Extremely Rare Event

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Lyme disease is caused by vascular dissemination of the bacteria Borrelia. In a 3D tissue‐engineered microvessel model, Borrelia extravasation across the blood–brain barrier is extremely rare, implying that neuroborreliosis is not caused via direct cytotoxicity.
Linus Wang, Zikai Xia, Anjan Singh, Bhavna Murarka, Nicole Baumgarth, John N. Aucott, Peter C. Searson   +6 more
wiley   +1 more source

There Goes the Neighbourhood—A Multi‐City Study Reveals Ticks and Tick‐Borne Pathogens Commonly Occupy Urban Green Spaces

Zoonoses and Public Health, Volume 72, Issue 3, Page 313-323, May 2025.
ABSTRACT Introduction Humans acquire tick‐borne pathogens (TBPs) from infected ticks contacted during outdoor activities. Outdoor activity is at its highest in urban green spaces, where the presence of tick populations has increasingly been observed. Consequently, more insight into factors influencing the presence of ticks therein is needed.
Jani J. Sormunen, Satu Kylänpää, Ella Sippola, Riikka Elo, Nosheen Kiran, Veli‐Matti Pakanen, Eva R. Kallio, Eero J. Vesterinen, Tero Klemola   +8 more
wiley   +1 more source