Results 71 to 80 of about 8,113 (209)

Bosentan and the endothelin system in congestive heart failure [PDF]

open access: bronze, 2000
Samer Ellahham   +4 more
openalex   +1 more source

Lower doses of bosentan in combination with sildenafil might be beneficial in pulmonary arterial hypertension

open access: yesResearch in Cardiovascular Medicine, 2015
Background: Endothelin-receptor-antagonist, bosentan, has been found to improve the functional capacity and cardiopulmonary hemodynamics in Pulmonary Arterial Hypertension (PAH).
Ahmad Amin   +4 more
doaj   +1 more source

Endothelin-1 receptors play a minor role in the protection against acute Trypanosoma cruzi infection in mice

open access: yesBrazilian Journal of Medical and Biological Research, 2007
Chagas' disease, caused by the protozoan Trypanosoma cruzi, is a major cause of cardiovascular disability in countries where it is endemic. Damage to the heart microvasculature has been proposed to be an important factor in the pathogenesis of heart ...
E. Roffê   +9 more
doaj  

Study on the comparison between Bosentan and Macitentan in the treatment of persistent pulmonary hypertension of the newborns, simultaneously on sildenafil: A randomized double-blinded non-inferiority parallel clinical trial

open access: yesPediatrics and Neonatology
Background: Persistent Pulmonary Hypertension of the newborn (PPHN) is characterized by sustained elevated Pulmonary Artery Pressure (PAP). Drug resistance and the adverse effects of current therapeutic agents warrant investigation of other targeted ...
Mandana Kashaki   +4 more
doaj  

[3H]Bosentan Binding to Human Coronary Artery

open access: bronze, 1995
M. R. Dashwood   +5 more
openalex   +1 more source

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