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Pulmonary Arterial Hypertension
New England Journal of Medicine, 2021 Abstract: This article discusses the pathophysiology, risk factors, clinical manifestations, diagnostics, and pharmacologic treatment of pulmonary arterial hypertension, as well as nursing considerations for caring for patients with this rare disease.
Paul M Hassoun
exaly +8 more sources
PULMONARY ARTERIAL HYPERTENSION [PDF]
Annals of Medicine, 2006 Pulmonary arterial hypertension is a disease of the small pulmonary arteries characterized by vascular narrowing and increased pulmonary vascular resistance, which eventually leads to right ventricular failure. Vasoconstriction, vascular proliferation, remodeling of the pulmonary vessels, and thrombosis are all contributing factors to the increased ...
Azad, Raiesdana, Joseph, Loscalzo
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Pulmonary arterial hypertension [PDF]
Internal and Emergency Medicine, 2009 In Internal and Emergency Medicine, Wu and coworkers [1] review the topic of pulmonary arterial hypertension. Overall, their article is sound and pertinent; however, some issues deserve comments. First, the value of chest radiography in the diagnostic process is somewhat overlooked.
Sheng Chin, Wu +7 more
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ERJ Open Research, 2023 Background Converging evidence from proteogenomic analyses prioritises thrombospondin-2 (TSP2) as a potential biomarker for idiopathic or heritable pulmonary arterial hypertension (PAH).
Anna M. Dittrich +7 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 Pulmonary arterial hypertension (PAH) is a disease characterized by elevated pulmonary vascular resistance and pulmonary artery pressure. Mortality remains high in severe cases despite significant advances in management and pharmacotherapy.
Jakob Körbelin +10 more
doaj +1 more source
ERJ Open Research, 2023 Background The 2022 ESC/ERS guidelines on pulmonary hypertension recommend noninvasive risk assessments based on three clinical variables during follow-up in patients with pulmonary arterial hypertension (PAH).
Jonna Ostermann +6 more
doaj +1 more source
Pulmonary Circulation, 2023 Approximately 25%–30% of patients diagnosed with idiopathic pulmonary arterial hypertension (PAH) have a clustered underlying Mendelian genetic cause and should be classified as heritable PAH (HPAH).
Kae‐Woei Liang +4 more
doaj +1 more source
Pulmonary arterial hypertension [PDF]
Breathe, 2005 Key pointsPAH is defined by RHC showing a pre-capillary PH.Clinical suspicion of PH should arise in the case of symptoms such as dyspnoea without overt signs of specific heart or lung disease.RHC is required to confirm the diagnosis of PAH, to assess the severity of the haemodynamic impairment and to test the vasoreactivity of the pulmonary circulation.
D, Montani +5 more
openaire +3 more sources
Pulmonary Arterial Hypertension
Critical Care Nursing Quarterly, 2007 Pulmonary arterial hypertension (PAH) is a rare and debilitating disease characterized by abnormal proliferation and contraction of pulmonary vascular smooth muscle cells. The resulting increase in pressure and pulmonary vascular resistance results in progressive right heart failure, low cardiac output, and ultimately death if left untreated.
José Luis, Puglisi +3 more
+7 more sources
BMC Pulmonary Medicine, 2017 Background Chronic inflammation emerges as a feature of the pathogenesis of pulmonary arterial hypertension (PAH) in experimental models. Alterations of circulating cell subsets have been observed in patients with PAH.
Lars Harbaum +9 more
doaj +1 more source