Results 21 to 30 of about 1,381,406 (265)

Impact of the updated hemodynamic definitions on diagnosis rates of pulmonary hypertension

Pulmonary Circulation, 2020
We evaluated whether updated pulmonary hypertension definitive criteria proposed in sixth World Symposium on Pulmonary Hypertension had an impact on diagnosis of overall pulmonary hypertension and pre-capillary and combined pre- and post-capillary ...
Seda Tanyeri, Ozgur Y. Akbal, Berhan Keskin, Aykun Hakgor, Ali Karagoz, Hacer Ceren Tokgoz, Cem Dogan, Zubeyde Bayram, Seyhmus Kulahcioglu, Emrah Erdogan, Ismail Balaban, Dogancan Ceneli, Rezzan Deniz Acar, Ibrahim H. Tanboga, Nihal Ozdemir, Cihangir Kaymaz   +15 more
doaj   +1 more source

Right ventricular function in scleroderma-related pulmonary hypertension [PDF]

, 2008
SSc-associated pulmonary arterial hypertension (PAH) has a poorer prognosis than that of other types of pulmonary hypertension. Recent echocardiographic and haemodynamic studies suggest that right ventriculer (RV) pump function and filling ...
A. Vonk Noordegraaf, Vonk Noordegraaf, Anton Vonk, Vonk Noordegraaf, A., Naeije, R., Naeije, Robert, R. Naeije   +5 more
core   +1 more source

Animal Models of Pulmonary Arterial Hypertension and Their Application in Drug Research

Shiyan dongwu yu bijiao yixue, 2023
Pulmonary arterial hypertension is a clinical syndrome characterized by pulmonary vascular remodeling causing increased vascular resistance, which will lead to right heart failure and even death if left untreated.
YU Jiahui, GONG Qian, ZHUANG Lenan
doaj   +1 more source

Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension

Pulmonary Circulation, 2019
Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Mattias Arvidsson, Abdulla Ahmed, Habib Bouzina, Göran Rådegran   +3 more
doaj   +1 more source

Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.

PLoS ONE, 2020
BACKGROUND:The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its ...
Ignacio Hernandez-Gonzalez, Jair Tenorio, Julian Palomino-Doza, Amaya Martinez Meñaca, Rafael Morales Ruiz, Mauro Lago-Docampo, María Valverde Gomez, Javier Gomez Roman, Ana Belén Enguita Valls, Carmen Perez-Olivares, Diana Valverde, Joan Gil Carbonell, Elvira Garrido-Lestache Rodríguez-Monte, Maria Jesus Del Cerro, Pablo Lapunzina, Pilar Escribano-Subias   +15 more
doaj   +1 more source

Transcription factors and potential therapeutic targets for pulmonary hypertension

Frontiers in Cell and Developmental Biology, 2023
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang, Naifu Wan, Fanpeng Gong, Xianfeng Wang, Lei Feng, Guizhu Liu   +5 more
doaj   +1 more source

Non-Invasive Pulmonary Artery Wave Intensity Analysis in Pulmonary Hypertension. [PDF]

, 2015
Pulmonary wave reflections are a potential hemodynamic biomarker for pulmonary hypertension (PH) and can be analyzed using wave intensity analysis (WIA). In this study we used pulmonary vessel area and flow obtained using cardiac magnetic resonance (CMR)
Moledina, S, Coghlan, JG, Quail, MA, Knight, DS, Quail, Michael A, Muthurangu, Vivek, Taylor, Andrew M, Steeden, Jennifer A, Taelman, Liesbeth, Moledina, Shahin, Segers, P, Knight, Daniel S, Taylor, AM, Steeden, JA, Taelman, L, Segers, Patrick, Coghlan, J Gerry, Muthurangu, V   +17 more
core   +1 more source

Anticoagulation in pulmonary arterial hypertension: a decision analysis

Pulmonary Circulation, 2019
Systemic anticoagulation may be beneficial in pulmonary arterial hypertension, but there is no randomized clinical trial data to guide therapeutic decision making, and current guidelines do not account for patient preferences or quality of life. Decision
Arun Jose, Mark H. Eckman, Jean M. Elwing   +2 more
doaj   +1 more source

Inspiratory flow patterns with dry powder inhalers of low and medium flow resistance in patients with pulmonary arterial hypertension

Pulmonary Circulation, 2021
Inhalation profiles to support use of dry powder inhalers for drug delivery in patients with pulmonary arterial hypertension have not been reported. We aimed to evaluate the inspiratory flow pattern associated with low and medium flow resistance dry ...
Mariana Faria-Urbina, Keith T. Ung, Laurie Lawler, Lawrence S. Zisman, Aaron B. Waxman   +4 more
doaj   +1 more source

Right ventriculo–pulmonary arterial uncoupling and poor outcomes in pulmonary arterial hypertension

Pulmonary Circulation, 2020
Right ventricular function critically affects the prognosis of patients with pulmonary arterial hypertension. We aimed to analyze the prognostic value of right ventricular indices calculated using magnetic resonance imaging and right heart ...
Toshitaka Nakaya, Hiroshi Ohira, Takahiro Sato, Taku Watanabe, Masaharu Nishimura, Noriko Oyama-Manabe, Masaru Kato, Yoichi M. Ito, Ichizo Tsujino   +8 more
doaj   +1 more source