Results 31 to 40 of about 173,364 (256)

Impact of the updated hemodynamic definitions on diagnosis rates of pulmonary hypertension

open access: yesPulmonary Circulation, 2020
We evaluated whether updated pulmonary hypertension definitive criteria proposed in sixth World Symposium on Pulmonary Hypertension had an impact on diagnosis of overall pulmonary hypertension and pre-capillary and combined pre- and post-capillary ...
Seda Tanyeri   +15 more
doaj   +1 more source

Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.

open access: yesPLoS ONE, 2020
BACKGROUND:The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its ...
Ignacio Hernandez-Gonzalez   +15 more
doaj   +1 more source

Animal Models of Pulmonary Arterial Hypertension and Their Application in Drug Research

open access: yesShiyan dongwu yu bijiao yixue, 2023
Pulmonary arterial hypertension is a clinical syndrome characterized by pulmonary vascular remodeling causing increased vascular resistance, which will lead to right heart failure and even death if left untreated.
YU Jiahui, GONG Qian, ZHUANG Lenan
doaj   +1 more source

Pulmonary Arterial Hypertension

open access: yesThe American Journal of the Medical Sciences, 2008
It is important for the general internist to maintain a high degree of suspicion for pulmonary hypertension in appropriate cases. This article reviews the definition and classification of pulmonary hypertension, epidemiology and risk factors, signs and symptoms, diagnostic approach, and treatment strategies.
Chin, Kelly M., Rubin, Lewis J.
openaire   +4 more sources

Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2019
Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Mattias Arvidsson   +3 more
doaj   +1 more source

Transcription factors and potential therapeutic targets for pulmonary hypertension

open access: yesFrontiers in Cell and Developmental Biology, 2023
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang   +5 more
doaj   +1 more source

Anticoagulation in pulmonary arterial hypertension: a decision analysis

open access: yesPulmonary Circulation, 2019
Systemic anticoagulation may be beneficial in pulmonary arterial hypertension, but there is no randomized clinical trial data to guide therapeutic decision making, and current guidelines do not account for patient preferences or quality of life. Decision
Arun Jose   +2 more
doaj   +1 more source

Inspiratory flow patterns with dry powder inhalers of low and medium flow resistance in patients with pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2021
Inhalation profiles to support use of dry powder inhalers for drug delivery in patients with pulmonary arterial hypertension have not been reported. We aimed to evaluate the inspiratory flow pattern associated with low and medium flow resistance dry ...
Mariana Faria-Urbina   +4 more
doaj   +1 more source

Right ventriculo–pulmonary arterial uncoupling and poor outcomes in pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2020
Right ventricular function critically affects the prognosis of patients with pulmonary arterial hypertension. We aimed to analyze the prognostic value of right ventricular indices calculated using magnetic resonance imaging and right heart ...
Toshitaka Nakaya   +8 more
doaj   +1 more source

Differences in health policies for drug availability in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension across Latin America

open access: yesPulmonary Circulation, 2022
Treatment for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension in Latin America differs between countries, with regard to disease etiology, health insurance coverage, and drug availability.
Mauricio Orozco‐Levi   +11 more
doaj   +1 more source

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