Results 51 to 60 of about 1,434 (169)

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi   +8 more
wiley   +1 more source

P53 genotype-independent anticancer effects of olibanum extract and 11-keto-beta-boswellic acid on human colorectal cancer cells

open access: yesPhytomedicine Plus
Background: Colorectal cancer (CRC) is the third most common cancer, and CRC-related mortality is increasing annually. A key regulator of the cell cycle and cell death, the p53 gene, is frequently found in patients with CRC as mutants.
Yeongju Bae, Junsik Seo, Wooyoung Jeong
doaj   +1 more source

A Botanical Mixture of Boswellia serrata, Commiphora myrrha, Propolis and Scutellaria baicalensis Reduces Expression of Inflammatory Chemokines in Canine Keratinocytes In Vitro

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
YSK‐AB, a botanical mixture, reduced nitric oxide production in RAW 264.7 cells and chemokine expression in canine keratinocytes, suggesting its potential as a natural therapeutic agent for inflammatory skin diseases in dogs. ABSTRACT Background Botanical ingredients can function as adjunctive therapies for managing inflammatory skin diseases ...
Danbee Ha   +3 more
wiley   +1 more source

Boswellic acid formulations are not suitable for treatment of pediatric high-grade glioma due to tumor promoting potential

open access: yesJournal of Traditional and Complementary Medicine
Background and aim: Pediatric high-grade gliomas (pedHGG) comprise a very poor prognosis. Thus, parents of affected children are increasingly resorting to complementary and alternative medicine (CAM), among those Boswellia extracts.
Maria Wiese   +12 more
doaj   +1 more source

Cancer Chemopreventive Effects of Gum Resin Hydrodistillates on Invasive Urothelial Cell Carcinoma: Report of a Case

open access: yesIntegrative Cancer Therapies, 2017
A 52-year-old Hispanic male presented with hematuria and was later diagnosed with a large invasive high-grade urothelial cell carcinoma (UCC) of the urinary bladder, but with ambiguous pT1/pT2 staging regarding musclaris propria invasion by UCC.
Ding Xia MD   +5 more
doaj   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

open access: yesAdvanced Science, Volume 13, Issue 21, 13 April 2026.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo   +9 more
wiley   +1 more source

ROLE OF BOSWELLIC ACID IN THE TREATMENT OF PEPTIC ULCER DISEASE [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2019
A peptic ulcer is a chronic disease. Its main features are the incompetent defense of the mucosal and the existence of the gastric juice. The two most important factors that disrupt the balance between the acid and the mucus are the Helicobacter pylori ...
Mai Sherif
doaj   +1 more source

A Multistep Computational Approach to Achieve a Complete Human 5‐Lipoxygenase Structure and Provide a Pharmacophore Model for Further Drug Design

open access: yesMolecular Informatics, Volume 45, Issue 3, March 2026.
Starting from incomplete structural information of 5‐lipoxygenase (5‐LOX), a multistep computational pipeline in silico led to powerful tools for the rational design and identification of novel chelator inhibitors. A reconstruction of the first full‐length 5‐LOX was performed and used to apply docking studies to enable to create a pharmacophore model ...
Lisa Lombardo   +3 more
wiley   +1 more source

Holy smoke in medieval funerary rites: chemical fingerprints of frankincense in southern Belgian incense burners. [PDF]

open access: yesPLoS ONE, 2014
Frankincense, the oleogum resin from Boswellia sp., has been an early luxury good in both Western and Eastern societies and is particularly used in Christian funerary and liturgical rites. The scant grave goods in late medieval burials comprise laterally
Jan Baeten   +4 more
doaj   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov   +16 more
wiley   +1 more source

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