Isomeric Differentiation of Four Triterpene Acids Using Full Collision Energy Ramp-MS2 Analysis
Triterpene acids, a subclass of acidic triterpenoids existing in their free state, are widely distributed throughout traditional Chinese medicine (TCM).
Li-juan WU +5 more
doaj +1 more source
Effect of Teucrium polium and Boswellia serrata extracts on cotaneus burn wound healing in Balb/C mice [PDF]
زمینه و هدف: از قدیم، چزکوهی و کندر برای ترمیم زخم سوختگی مورد استفاده قرار می گرفتند، ولی این موضوع از نظر علمی مورد بررسی قرار نگرفته است. این مطالعه به منظور بررسی اثرات درمانی ترکیب چز کوهی و کندر بر فرآیند التیام زخم سوختگی در موش Balb/c انجام شد ...
Ansari Samani, Roya. +6 more
core
Antibacterial hydrogel: The sniper of chronic wounds
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian +6 more
wiley +1 more source
Glycyrrhetinic acid and its derivatives as inhibitors of poly(ADP-ribose)polymerases 1 and 2, apurinic/apyrimidinic endonuclease 1 and DNA polymerase β [PDF]
Aim. For strengthening the efficiency of monofunctional alkylating antineoplastic drugs it is important to lower the capacity of base excision repair (BER) system which corrects the majority of DNA damages caused by these reagents.
Ilina E. S. +8 more
core +3 more sources
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia +4 more
wiley +1 more source
A study of the clinical efficacy of frankincense in the acute phase of ischemic stroke [PDF]
Background and aims: Ischemic stroke is the most common type of stroke and its most important symptoms are paralysis and movement disorders. Therefore, finding a method for treating this disorder is greatly important.
Azizi, Mahmoud. +4 more
core
The role of phospholipid as a solubility- and permeability-enhancing excipient for the improved delivery of the bioactive phytoconstituents of Bacopa monnieri [PDF]
In an attempt to improve the solubility and permeability of Standardized Bacopa Extract (SBE), a complexation approach based on phospholipid was employed.
Bobde, Yamini S +6 more
core +2 more sources
An Updated Review of the Anticancer Mechanisms and Therapeutic Potential of Naringenin
Naringenin is a bioactive compound widely distributed in the citrus family, belonging to polyphenols known for several health‐promoting properties, including anticancer activity. Several evidence‐based reports have proved that Naringenin can reduce tumorigenesis via inhibiting NRF2, TNF, NF‐κB, NR3C1, P13K/AKT, TGF‐β1/Smad3, and Bcl‐2 expression ...
Ahmad Mujtaba Noman +13 more
wiley +1 more source
State of affairs in use of steroids in diffuse intrinsic pontine glioma: an international survey and a review of the literature [PDF]
Children diagnosed with diffuse intrinsic pontine glioma (DIPG) face a dismal prognosis, with severe neurologic deterioration and inevitable death at a median of 9 months from diagnosis.
Cruz, O +4 more
core +1 more source
Natural products targeting tumour angiogenesis
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu +2 more
wiley +1 more source

