Results 41 to 50 of about 223,094 (313)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The original Bottleneck module and the improved Bottleneck module.

open access: yes, 2022
A: original Bottleneck module. B:depthwise convolution. C: improved Bottleneck module.
Leilei Wang (154118)   +3 more
core   +1 more source

Genetic differentiation and bottleneck effects in the malaria vectors Anopheles farauti and Anopheles punctulatus after an LLIN‐based vector control program in Papua New Guinea

open access: yesEcology and Evolution
Implementation of long‐lasting insecticide‐treated net (LLIN) programs to control human malaria transmission leads to substantial reductions in the abundance of Anopheles mosquitoes, but the impact on the population genetic structure of the malaria ...
John B. Keven   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Effects of pavement surface deformations on traffic flow

open access: yesTransport, 2019
Pavement surface deformations have a significant effect on speed profile of vehicles and traffic flow conditions. These deformations limit driving properties and increase vehicle operation and maintenance costs.
Metin Mutlu Aydin, Ali Topal
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Entrepreneurship performance of Vietnam

open access: yesSerbian Journal of Management, 2022
The study aims to measure entrepreneurship performance of Vietnam in comparison to Asiancountries by applying the Global Entrepreneurship Development Index (GEDI) and then employedthe Penalty for Bottleneck (PFB) methodology to allocate priority policies
Nguyen Thi Thu Ha, Lam Ba Hoa
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

PHONON BOTTLENECK IN PARAMAGNETIC CRYSTALS [PDF]

open access: yes, 1965
A unified treatment of phonon bottleneck theory is given, using a thermodynamic method which includes both the direct and Orbach processes. The key parameter is the phonon relaxation time, which is calculated in a variety of cases, including several in ...
STONEHAM, AM
core  

Improved bottleneck domination algorithms [PDF]

open access: yes, 2006
W.C.K. Yen introduced BOTTLENECK DOMINATION and BOTTLENECK INDEPENDENT DOMINATION. He presented an O(nlogn+m)-time algorithm to compute a minimum bottleneck dominating set.
Kloks, Ton   +3 more
core   +1 more source

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