Results 61 to 70 of about 3,555,401 (304)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Fermionic Corrections to the Three-Loop Matching Coefficient of the Vector Current
, 2006 In this paper we consider the matching coefficient of the vector current between Quantum Chromodynamics (QCD) and Non-Relativistic QCD (NRQCD) to three-loop order in perturbation theory.
Anastasiou +59 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Self-protected electrodes limit field-emission current [PDF]
, 1975 One cathode includes array of square-shaped conductor columns. Columns are electrically interconnected by conducting plate on bottom. Each column provides field-emission current. Another cathode includes array of rodlike conductors.
Lees, W. L.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Evidence of the selection of tidal streams by northern rock sole (Lepidopsetta polyxystra) for transport in the eastern Bering Sea [PDF]
, 2009 Depth data from archival tags on northern rock sole (Lepidopsetta polyxystra) were examined to assess whether fish used tidal currents to aid horizontal migration.
Nichol, Daniel G., Somerton, David A.
core
$b \to s \gamma$ Decay and Right-handed Top-bottom Charged Current
, 1995 We introduce an anomalous top quark coupling (right-handed current) into Standard Model Lagrangian. Based on this, a more complete calculation of $b \to s\gamma $ decay including leading log QCD corrections from $m_{top}$ to $M_W$ in addition to ...
A.J. Buras +34 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
RecyclingThis research introduces an extended processing method for increasing the possibility of valorizing processed IBA (pr.IBA), which is currently only used as a construction material in landfill sites, considering its immense potential in valuable metal and
Ida Bagus Gede Sumbranang Adhiwiguna +5 more
doaj +1 more source