Results 41 to 50 of about 86,912 (265)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Cyclic Pockmark Formation Linked to Plio‐Pleistocene Sea‐Level Rise on the Chatham Rise, New Zealand
Geochemistry, Geophysics, GeosystemsPockmarks are geomorphological depressions on the seafloor in various underwater environmental settings. They are commonly linked to fluid release from subsurface reservoirs; however, the processes involved, fluid types, and relative timing of their ...
Fynn Warnke +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Flow morphology in bottom-propagating gravity currents over immersed obstacles
AIP Advances, 2020 The interaction of bottom-propagating gravity currents with immersed obstacles in the path of the lock-exchange configuration was numerically investigated based on large eddy simulations.
Ching-Sen Wu, Huei-Tau Ouyang
doaj +1 more source
Journal of Marine Science and Engineering, 2022 The world’s largest living glass sponge reefs, located in the Hecate Strait and Queen Charlotte Sound off British Columbia, are impacted by bottom contact fishing gear.
Guoqi Han +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A complete and continuous core record of deep-water mass transport deposits
Frontiers in Marine ScienceMass transport deposits are a fundamental component of deep-water sedimentary systems and play a crucial role in the transportation of sediments from continental slopes to deep-sea basins.
Cong Cheng +11 more
doaj +1 more source
Multi-Scale Influence of Flexible Submerged Aquatic Vegetation (SAV) on Estuarine Hydrodynamics
Journal of Marine Science and Engineering, 2022 Bottom friction is an important process in coastal and estuarine environments because it can reduce wave heights and moderate tidal currents. When modeling large systems with spatially varying hydraulic properties, bottom friction values are commonly ...
Elizabeth R. Holzenthal +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source