Results 61 to 70 of about 458,745 (304)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Cyclic Pockmark Formation Linked to Plio‐Pleistocene Sea‐Level Rise on the Chatham Rise, New Zealand
Geochemistry, Geophysics, GeosystemsPockmarks are geomorphological depressions on the seafloor in various underwater environmental settings. They are commonly linked to fluid release from subsurface reservoirs; however, the processes involved, fluid types, and relative timing of their ...
Fynn Warnke +4 more
doaj +1 more source
A complete and continuous core record of deep-water mass transport deposits
Frontiers in Marine ScienceMass transport deposits are a fundamental component of deep-water sedimentary systems and play a crucial role in the transportation of sediments from continental slopes to deep-sea basins.
Cong Cheng +11 more
doaj +1 more source
Journal of Marine Science and Engineering, 2022 The world’s largest living glass sponge reefs, located in the Hecate Strait and Queen Charlotte Sound off British Columbia, are impacted by bottom contact fishing gear.
Guoqi Han +3 more
doaj +1 more source
Gravity currents in rotating, wedge-shaped, adverse channels [PDF]
, 2013 Results are presented from a series of parametric experimental and analytical studies of the behaviour of dense gravity currents along rotating, up-sloping, wedge-shaped channels.
Cuthbertson, A. J. S. +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
General characteristics of current in front of Port Said, Egypt
Egyptian Journal of Aquatic Research, 2017 This paper is a preliminary investigation of the general characteristics of the current in front of the coastal Mediterranean city: Port Said, Egypt. The study of the current regime in front of Port Said helps environmental engineers to tackle problems ...
Mohamed S. Elsharkawy +2 more
doaj +1 more source
The surface states of topological insulators - Dirac fermion in curved two dimensional spaces
, 2009 The surface of a topological insulator is a closed two dimensional manifold. The surface states are described by the Dirac Hamiltonian in curved two dimensional spaces.
Dung-Hai Lee, M. B. Green
core +1 more source
The Dynamics of Flat Surface Internal Geophysical Waves with Currents [PDF]
, 2016 A two-dimensional water wave system is examined consisting of two discrete incompressible fluid domains separated by a free common interface. In a geophysical context this is a model of an internal wave, formed at a pycnocline or thermocline in the ocean.
Compelli, Alan, Ivanov, Rossen
core +3 more sources
Dynamics of bottom currents in a small lake1 [PDF]
Limnology and Oceanography, 1987 The dynamics of bottom currents in Baldeggersee, Switzerland, were investigated with a specially designed recording current meter sensitive to current velocities of 0.3–2.5 cm s−1. Supporting information was obtained from thermistor‐chain temperature recordings and from records of atmospheric boundary‐layer parameters measured in the center of the lake.
U. Lemmin, D. M. Imboden
openaire +1 more source