Results 81 to 90 of about 458,745 (304)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Flow of Antarctic Bottom water from the Vema Channel

open access: yesGeoscience Letters, 2020
We analyze measurements of bottom currents and thermohaline properties of water north of the Vema Channel with the goal to find pathway continuations of Antarctic Bottom Water flow from the Vema Channel into the Brazil Basin. The analysis is based on CTD/
Eugene G. Morozov   +2 more
doaj   +1 more source

The influence of mask thickness on charging damage during overetching [PDF]

open access: yes, 1997
Feature-scale charging simulations during gate electrode overetching in high-density plasmas reveal that the thickness of the insulating mask plays a critical role in charging damage. When thinner masks are used, the electron irradiance of the conductive
Giapis, Konstantinos P.   +1 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Paleogeographic approach for the oil and gas potential assessment of the Khadum Formation (Lower Oligocene) in Pre-Caucasus basin

open access: yesGeoresursy
Authors used the paleogeographic approach to identify the different facies generation potential, mark out the areas with the highest organic matter and its types, analyse the reservoir quality for oil and gas potential assessment of the Pre-Caucasus ...
A. N. Stafeev   +7 more
doaj   +1 more source

High Resolution 3-D Finite-Volume Coastal Ocean Modeling in Lower Campbell River and Discovery Passage, British Columbia, Canada

open access: yesJournal of Marine Science and Engineering, 2014
The 3-D unstructured-grid, Finite-Volume Coastal Ocean Model (FVCOM) was used to simulate the flows in Discovery Passage including the adjoining Lower Campbell River, British Columbia, Canada.
Yuehua Lin, David B. Fissel
doaj   +1 more source

Engineering spin-orbit torque in Co/Pt multilayers with perpendicular magnetic anisotropy

open access: yes, 2015
To address thermal stability issues for spintronic devices with a reduced size, we investigate spin-orbit torque in Co/Pt multilayers with strong perpendicular magnetic anisotropy.
Huang, Kuo-Feng   +3 more
core   +1 more source

Bottom dissipation of subinertial currents at the Atlantic zonal boundaries [PDF]

open access: yes, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90515/1/jgr_bbldiss_wrightetal_2012 ...
Arbic   +28 more
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Erosion and deposition in interplain channels of the Maury channel system [PDF]

open access: yes, 1981
Large turbidity currents originating on the insular margin of southern lceland have flowed clown a 2 500 km-long pathway comprising rise valleys, unchanneled plains and segments of erosional and depositional deep-sea channels that are collectively called
Hollister, C. D.   +2 more
core   +1 more source

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