Results 51 to 60 of about 27,676 (260)
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Object-Based Mapping of Coral Reef Habitats Using Planet Dove Satellites
High spatial resolution benthic habitat information is essential for coral reef protection and coastal environmental management. Satellite-based shallow benthic composition mapping offers a more efficient approach than traditional field measurements ...
Jiwei Li +3 more
doaj +1 more source
Reflection of Pulses from the Ocean Bottom [PDF]
The macroscopic physical properties of the ocean bottom have received considerable attention in recent years. Two important points of view which serve as motivation for such studies are acoustical and geological in nature. Experimental records of explosion pulses were obtained before and after reflection from the relatively smooth and level Hatteras ...
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Autonomous Coral Reef Survey in Support of Remote Sensing
An autonomous surface vehicle instrumented with optical and acoustical sensors was deployed in Kane'ohe Bay, HI, U.S.A., to provide high-resolution, in situ observations of coral reef reflectance with minimal human presence.
Steven G. Ackleson +4 more
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Volcanic ash deposition can influence coral reef ecosystems, yet its impacts remain poorly quantified due to the rarity and limited field observations. Here, we combined Sentinel-2 imagery with a shallow-water radiative transfer model to retrieve bottom ...
Yunhan Ma +5 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
To address the insufficient characterization of vertical heterogeneity in potato canopy leaf nitrogen content (LNC), this study developed a layer-specific LNC estimation framework based on canopy hyperspectral reflectance, fractional-order derivative ...
Ming Jin +9 more
doaj +1 more source

