Results 81 to 90 of about 197,944 (293)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Air Pressure and the Coefficient of Restitution of a Ball

open access: yesInternational Scholastic Journal of Science, 2009
The relationship between the internal air pressure and the coefficient of restitution was investigated for an inflated rubber ball. The ball was dropped and its position was tracked with a motion detector.
Kareem Osman, Boree Sophie Kim
doaj  

Bounce Universe and Black Holes from Critical Einsteinian Cubic Gravity

open access: yes, 2017
We show that there exists a critical point for the coupling constants in Einsteinian cubic gravity where the linearized equations on the maximally-symmetric vacuum vanish identically. We construct an exact isotropic bounce universe in the critical theory
Feng, Xing-Hui   +3 more
core   +1 more source

Big Bounce Baryogenesis [PDF]

open access: yesJournal of Cosmology and Astroparticle Physics, 2020
We explore the possibility of an Ekpyrotic contraction phase harbouring a mechanism for Baryogenesis. A Chern-Simons coupling between the fast-rolling Ekpyrotic scalar and the Standard Model Hypercharge gauge field enables the generation of a non-zero helicity during the contraction phase.
openaire   +3 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Bounce of a Basketball in a Puddle: Depth of Water and Coefficient of Restitution

open access: yesInternational Scholastic Journal of Science, 2015
A basketball was dropped into puddles with depths of water ranging from zero to 4 mm from a height of 1.1 m to investigate the relationship between the depth of water in a puddle and the coefficient of restitution with measurements of the drop height and
Chankyu Han
doaj  

Theoretical bounce resonance diffusion coefficient for waves generated near the equatorial plane

open access: yesGeophysical Research Letters, 2016
Theoretical bounce resonance diffusion coefficient for waves generated near the equatorial plane with arbitrary wave normal angle distributions is derived.
X. Tao, X. Li
doaj   +1 more source

A Matter Bounce By Means of Ghost Condensation

open access: yes, 2010
Assuming the existence of a scalar field which undergoes "ghost condensation" and which has a suitably chosen potential, it is possible to obtain a non-singular bouncing cosmology in the presence of regular matter and radiation.
Brandenberger, Robert H.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Perturbation analysis of trapped-particle dynamics in axisymmetric dipole geometry

open access: yes, 2010
The perturbation analysis of the bounce action-angle coordinates $(J,\zeta)$ for charged particles trapped in an axisymmetric dipole magnetic field is presented.
A. J. Brizard   +5 more
core   +1 more source

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