Results 111 to 120 of about 394,492 (288)

Interaction-Induced Multiparticle Bound States in the Continuum

Physical Review Letters
Bound states in the continuum (BICs) are localized modes residing in the radiation continuum. They were first predicted for single-particle states, and became a general feature of many wave systems. In many-body quantum physics, it is still unclear what would be a close analog of BICs, and whether interparticle interaction may induce BICs.
Boning Huang, Yongguan Ke, Honghua Zhong, Yuri S. Kivshar, Chaohong Lee   +4 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Quantum decay and amplification in a non-Hermitian unstable continuum

, 2016
The decay of a bound state weakly-coupled to a non-Hermitian tight-binding unstable continuum, i.e. a continuum of states comprising energies with positive imaginary part, is theoretically investigated.
Longhi, Stefano
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

All-dielectric structural coloration empowered by bound states in the continuum

Nanophotonics
The technological requirements of low-power and high-fidelity color displays have been instrumental in driving research into advanced coloration technologies.
Zheng Hong, Hu Haiyang, Weber Thomas, Wang Juan, Nan Lin, Zou Bingsuo, Maier Stefan A., Tittl Andreas   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Bound States in the Continuum in Fiber Bragg Gratings [PDF]

ACS Photonics, 2019
Optical fibers typically confine light through total internal reflection or through photonic bandgaps. Here we show that light can be perfectly guided in optical fibers through a different mechanism based on bound states in the continuum (BICs). In fibers with periodic Bragg gratings, we predict bona fide BICs in pure-polarization modes, as well as ...
Xingwei Gao, Bo Zhen, Marin Soljačić, Hongsheng Chen, Chia Wei Hsu   +4 more
openaire   +2 more sources

A hierarchy of bound states in the 1D ferromagnetic Ising chain CoNb$_2$O$_6$ investigated by high resolution time-domain terahertz spectroscopy

, 2014
Kink bound states in the one dimensional ferromagnetic Ising chain compound CoNb$_2$O$_6$ have been studied using high resolution time-domain terahertz spectroscopy in zero applied magnetic field.
Aguilar, R. Valdés, Armitage, N. P., Cava, R. J., Ghosh, A., Koohpayeh, S. M., Krizan, J., McQueen, T. M., Morris, C. M., Tchernyshyov, O.   +8 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source