Results 71 to 80 of about 774 (212)

Critical states embedded in the continuum

New Journal of Physics, 2015
We introduce a class of critical states which are embedded in the continuum (CSC) of a one-dimensional optical waveguide array with one non-Hermitian defect. These states are on the verge of being fractal and have real propagation constants.
M Koirala, A Yamilov, A Basiri, Y Bromberg, H Cao, T Kottos   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Topological evolution of band degeneracies and bound states in the continuum in anisotropic photonic crystal slabs

New Journal of Physics
Topological degeneracies, such as Dirac or Weyl points and exceptional points, play a vital role in photonics and metamaterials due to their unique topological characteristics.
Xin Gao, Ze-Huan Zheng, Qilin Duan, Huanyang Chen, Ying Chen   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

All-dielectric structural coloration empowered by bound states in the continuum

Nanophotonics
The technological requirements of low-power and high-fidelity color displays have been instrumental in driving research into advanced coloration technologies.
Zheng Hong, Hu Haiyang, Weber Thomas, Wang Juan, Nan Lin, Zou Bingsuo, Maier Stefan A., Tittl Andreas   +7 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Bound states in the continuum in a chain of coupled Mie resonators with structural disorder: theory and experiment

Nanophotonics
We study the impact of structural disorder on a radiative lifetime of symmetry-protected bound state in the continuum (BIC) and a bright mode in a one-dimensional periodic chain of coupled Mie resonators. Through experimental, simulation, and theoretical
Nazarov Ravshanjon, Khanabiev Denis, Chernysheva Elizaveta, Dudnikova Alexandra, Istomin Vyacheslav, Sidorenko Mikhail, Shi Jinhui, Maslova Ekaterina, Bogdanov Andrey, Kondratenko (Sadrieva) Zarina   +9 more
doaj   +1 more source

Bound States in the Continuum through Environmental Design

Physical Review Letters, 2019
7 pages, 3 ...
Alexander Cerjan, Chia Wei Hsu, Mikael C. Rechtsman   +2 more
openaire   +4 more sources