Results 91 to 100 of about 8,334,111 (303)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Hierachical Infrastrucutre for SOC Test Management [PDF]
HD2BIST - a complete hierarchical framework for BIST scheduling, data-patterns delivery, and diagnosis of complex systems - maximizes and simplifies the reuse of built-in test architectures.
Zorian Y. +4 more
core +1 more source
The Effects of Unemployment on Economic Growth in Greece. An ARDL Bound Test Approach.
The aim of this paper is to investigate the relationship between unemployment rate, economic growth and inflation rate in Greece, using annual data covering the period 1995-2015.
Nikolaos Dritsakis , Pavlos Stamatiou
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
STARC-5. Fragebogen für Empowerment und Resilienz
STARC-5 eignet sich mit 5 analytisch entwickelten Dimensionen (Self-esteem/ Selbstvertrauen, Trust/Optimismus, Affective resilience/Affektive Resilienz, Reliable problem solving/Problemlösekompetenz, Cognitive strength/Kognitive Stärke) und insgesamt 39 ...
Himmer-Gurdan, S. B.
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Onward Bound: The First Fifty Years of Outward Bound Australia
Onward Bound: — the first 50 years of Outward Bound Australia traces the founding and development of this unique, non-profit, non-government organization. From its earnest beginnings in a climate of post war cultural change, Outward Bound Australia (OBA)
Klaebe, Helen G.
core
Influence of Lipschitz bounds on the speed of global optimization
Global optimization methods based on Lipschitz bounds have been analyzed and applied widely to solve various optimization problems. In this paper a bound for Lipschitz function is proposed, which is computed using function values at the vertices of a ...
Remigijus Paulavičius +1 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

