Results 81 to 90 of about 945,073 (267)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The Effects of Unemployment on Economic Growth in Greece. An ARDL Bound Test Approach.

open access: yesRomanian Economic Journal, 2016
The aim of this paper is to investigate the relationship between unemployment rate, economic growth and inflation rate in Greece, using annual data covering the period 1995-2015.
Nikolaos Dritsakis , Pavlos Stamatiou
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Nonuniform Bound to an Independent Test in High Dimensional Data Analysis via Stein’s Method

open access: yesJournal of Probability and Statistics, 2019
The Berry-Esseen bound for the random variable based on the sum of squared sample correlation coefficients and used to test the complete independence in high diemensions is shown by Stein’s method.
Nahathai Rerkruthairat
doaj   +1 more source

Influence of Lipschitz bounds on the speed of global optimization

open access: yesTechnological and Economic Development of Economy, 2012
Global optimization methods based on Lipschitz bounds have been analyzed and applied widely to solve various optimization problems. In this paper a bound for Lipschitz function is proposed, which is computed using function values at the vertices of a ...
Remigijus Paulavičius   +1 more
doaj   +1 more source

Reducing the Costs of Bounded-Exhaustive Testing [PDF]

open access: yes, 2009
Bounded-exhaustive testing is an automated testing methodology that checks the code under test for all inputs within given bounds: first the user describes a set of test inputs and provides test oracles that check test outputs; then the tool generates all the inputs, executes them on the code under test, and checks the outputs; and finally the user ...
Vilas Jagannath   +3 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Evaluating Economic Resilience: Lighting the Nexus Between Turkish Imports and Foreign Exchange Reserves

open access: yesStudies in Business and Economics
This study investigates the relationship between Türkiye’s imports and foreign exchange reserves, aiming to provide detailed information about Türkiye’s economic dynamics by using data from October 2002 to July 2022 and several robust methodologies ...
Tekin Bilgehan
doaj   +1 more source

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